脂滴的生命周期。
The life of lipid droplets.
作者信息
Walther Tobias C, Farese Robert V
机构信息
Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, Martinsried, Germany.
出版信息
Biochim Biophys Acta. 2009 Jun;1791(6):459-66. doi: 10.1016/j.bbalip.2008.10.009. Epub 2008 Nov 7.
Abstract
Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells. Here we examine what we know of the life of lipid droplets. We review emerging data concerning their cellular biology and present our thoughts on some of the most salient questions for investigation.
摘要
脂滴是细胞内研究最少的细胞器。长期以来，这些动态且引人注目的细胞器一直被视为简单的脂质储存库，而最近它们被发现参与了许多生物学过程，直到现在我们才开始深入了解它们在细胞中迷人的生命历程。在此，我们审视我们所了解的脂滴的生命历程。我们回顾了有关其细胞生物学的新数据，并就一些最突出的待研究问题阐述我们的观点。
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