腮腺肿瘤：细针穿刺活检和/或冰冻切片检查。

Parotid tumors: fine-needle aspiration and/or frozen section.

作者信息

Zbären Peter, Guélat Dominique, Loosli Heinz, Stauffer Edouard

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital, Berne, Switzerland.

出版信息

Otolaryngol Head Neck Surg. 2008 Dec;139(6):811-5. doi: 10.1016/j.otohns.2008.09.013.

DOI:10.1016/j.otohns.2008.09.013

PMID:19041508

Abstract

OBJECTIVE

The purpose of this study was to analyze and compare the value of fine-needle aspiration cytology (FNAC) and frozen section (FS) analysis in the assessment of parotid gland tumors.

STUDY DESIGN

Chart review and cross-sectional analysis.

SUBJECTS AND METHODS

FNAC and FS analysis of 110 parotid tumors, 68 malignancies and 42 benign tumors, were analyzed and compared with the final histopathologic diagnosis.

RESULTS

The accuracy, sensitivity, and specificity of FNAC in detecting malignant tumors were 79 percent, 74 percent, and 88 percent, respectively. On FS analysis, the accuracy, sensitivity, and specificity in detecting malignant tumors were 94 percent, 93 percent, and 95 percent, respectively. The histologic tumor type was correctly diagnosed by FNAC and FS in 27 of 42 (64%) and 39 of 42 (93%) benign tumors, respectively, and in 24 of 68 (35%) and 49 of 68 (72%) malignant neoplasms, respectively.

CONCLUSION

The current analysis showed a superiority of FS compared with FNAC regarding the diagnosis of malignancy and tumor typing. FNAC alone is not prone to determine the surgical management of parotid malignancies.

摘要

目的

本研究旨在分析和比较细针穿刺细胞学检查（FNAC）和冰冻切片（FS）分析在腮腺肿瘤评估中的价值。

研究设计

病历回顾和横断面分析。

研究对象与方法

对110例腮腺肿瘤（68例恶性肿瘤和42例良性肿瘤）进行FNAC和FS分析，并与最终组织病理学诊断结果进行比较。

结果

FNAC检测恶性肿瘤的准确性、敏感性和特异性分别为79%、74%和88%。在FS分析中，检测恶性肿瘤的准确性、敏感性和特异性分别为94%、93%和95%。在42例良性肿瘤中，FNAC和FS分别正确诊断出27例（64%）和39例（93%）的组织学肿瘤类型；在68例恶性肿瘤中，分别正确诊断出24例（35%）和49例（72%）。