Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc?

作者信息

Sauvageau Guy, Perreault Claude

机构信息

Laboratory of Molecular Genetics of Stem Cells, Institute for Research in Immunology and Cancer (IRIC), C.P. 6128 succursale Centre-Ville, Montréal, Québec H3C 3J7, Canada.

出版信息

Cell Stem Cell. 2008 Dec 4;3(6):579-80. doi: 10.1016/j.stem.2008.11.003.

DOI:10.1016/j.stem.2008.11.003

PMID:19041771

Abstract

c-myc is a key regulator of hemopoietic stem cell (HSC) activity. In this issue of Cell Stem Cell, Laurenti et al. (2008) show that c-myc and N-myc control HSC survival and link this finding to the regulation of granzyme B expression.

摘要