Abbasi Naheed, Firoz Bahar, Bossenbroek Nicole M, Meehan Shane A, Kamino Hideko, Franks Andrew G
Department of Dermatology, New York University, USA.
Dermatol Online J. 2008 Oct 15;14(10):11.
A 37-year-old woman presented with a one-year history of asymptomatic, red-brown patches and plaques on the abdomen and extremities, in the context of Raynaud phenomenon and anti-centromere antibodies. Two biopsy specimens confirmed the diagnosis of inflammatory morphea. Even in the absence of initial symptoms to support systemic disease, patients presenting with morphea in the setting of Raynaud phenomenon or anti-centromere antibodies deserve close surveillance for the possibility of CREST syndrome and systemic sclerosis.
一名37岁女性,腹部和四肢出现无症状的红棕色斑块和斑片已有一年,同时伴有雷诺现象和抗着丝点抗体。两份活检标本确诊为炎症性硬斑病。即使最初没有支持全身性疾病的症状,但在出现雷诺现象或抗着丝点抗体的情况下发生硬斑病的患者,仍值得密切监测是否有CREST综合征和系统性硬化症的可能。