Brau R H, Betancourt A J, Vásquez R, Brau R R, Colberg R
Neurosurgery Department, School of Medicine, University of Puerto Rico, PO Box 365067, San Juan, PR.
P R Health Sci J. 2008 Dec;27(4):315-21.
Carotid endarterectomy is one of the main surgical procedures used for carotid stenosis and its recurrence. Besides the setting of a randomized controlled trial for asymptomatic and symptomatic carotid artery stenosis, there is little information about the rate of restenosis after carotid endarterectomy in Hispanics. The purpose of this study is to describe the results of carotid endarterectomy on the basis of restenosis in a Hispanic population.
A retrospective revision of 47 endarterectomies performed on 43 patients by a single surgeon at the VA Caribbean Health Care System and Pavia Hospital, during an eight year period (1990-1998), was conducted. Information about endarterectomies, restenosis and known risk factors for carotid stenosis were obtained from medical records.
Of the 43 patients, 31 were male (72%) and 12 female (28%), with a mean age of 67.9 years. Re-operations for recurrent carotid stenosis were performed in 2 patients (4.7%). Restenosis cases were asymptomatic, hence diagnosed through followup ultrasound Duplex studies and confirmed by angiography after 3 and 4 years of the first surgical procedure. The degree of restenosis (70% to 99%) after the initial endarterectomy was 4.3%. The major risk factors found among patients were hypertension (58%), hypercholesterolemia (50%), smoking (46%), and alcohol (34%).
Carotid endarterectomy with primary closure is safe and durable. Repeated surgery using patch grafts in this Hispanic population was also safe. The concordance of risk factors and incidence of carotid stenosis correlated well with other studies.
颈动脉内膜切除术是治疗颈动脉狭窄及其复发的主要外科手术之一。除了针对无症状和有症状颈动脉狭窄开展随机对照试验外,关于西班牙裔人群颈动脉内膜切除术后再狭窄率的信息很少。本研究的目的是基于西班牙裔人群的再狭窄情况描述颈动脉内膜切除术的结果。
对一名外科医生在1990年至1998年的八年期间,于弗吉尼亚加勒比医疗系统和帕维亚医院为43例患者实施的47例内膜切除术进行回顾性分析。从病历中获取有关内膜切除术、再狭窄以及已知的颈动脉狭窄危险因素的信息。
43例患者中,男性31例(72%),女性12例(28%),平均年龄67.9岁。2例患者(4.7%)因复发性颈动脉狭窄接受了再次手术。再狭窄病例无症状,因此通过随访超声双功检查诊断,并在首次手术3年和4年后通过血管造影证实。初次内膜切除术后的再狭窄程度(70%至99%)为4.3%。患者中发现的主要危险因素为高血压(58%)、高胆固醇血症(50%)、吸烟(46%)和饮酒(34%)。
一期缝合的颈动脉内膜切除术安全且持久。在这一西班牙裔人群中使用补片移植进行再次手术也是安全的。危险因素与颈动脉狭窄发生率的一致性与其他研究结果相关性良好。