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关于认知行为疗法对创伤后应激障碍有效性的系统评价。

A systematic review on the effectiveness of cognitive behavioral therapy for posttraumatic stress disorder.

作者信息

Mendes Deise D, Mello Marcelo Feijó, Ventura Paula, Passarela Cristiane De Medeiros, Mari Jair de Jesus

机构信息

Universidade Federal de São Paulo, Departamento de Psiquiatria, Brazil.

出版信息

Int J Psychiatry Med. 2008;38(3):241-59. doi: 10.2190/PM.38.3.b.

Abstract

OBJECTIVE

Cognitive behavioral therapy (CBT) is the most common psychotherapy approach for the treatment of PTSD. Nevertheless, previous reviews on the efficacy of several types of psychotherapy were unable to detect differences between CBT and other psychotherapies. The purpose of this study was to conduct systematic review on the efficacy ofCBT in comparison with studies that used other psychotherapy techniques.

METHOD

Databases were searched using the following terms: posttraumatic stress disorder/stress disorder, treatment/psychotherapy/behavior cognitive therapy, randomized trials, and adults. Randomized clinical trials published between 1980 and 2005 and that compared CBT with other treatments for PTSD was included. The main outcomes were remission, clinical improvement, dropout rates and changes in symptoms.

RESULTS

The 23 clinical trials included in the review comprised 1923 patients: 898 in the treatment group and 1,025 in the control group. CBT had better remission rates than EMDR (RR = 0.35; 95% CI: 0.16; 0.79; p = 0.01) or supportive therapies (RR = 0.43; 95% CI: 0.25; 0.74; p = 0.002, completer analysis). CBT was comparable to Exposure Therapy (ET) (RR = 0.90; 95% CI: 0.58; 1.40; p = 0.64), and cognitive therapy (CT) (RR = 1.01; 95% CI: 0.67; 1.51; p = 0.98) in terms of efficacy and compliance.

CONCLUSIONS

These findings suggest that specific therapies, such as CBT, exposure therapy and cognitive therapy are equally effective, and more effective than supportive techniques in the treatment of PTSD.

摘要

目的

认知行为疗法(CBT)是治疗创伤后应激障碍(PTSD)最常用的心理治疗方法。然而,先前关于几种心理治疗方法疗效的综述未能发现CBT与其他心理治疗方法之间的差异。本研究的目的是对CBT与使用其他心理治疗技术的研究的疗效进行系统评价。

方法

使用以下术语检索数据库:创伤后应激障碍/应激障碍、治疗/心理治疗/行为认知疗法、随机试验和成年人。纳入1980年至2005年间发表的将CBT与PTSD的其他治疗方法进行比较的随机临床试验。主要结局包括缓解、临床改善、脱落率和症状变化。

结果

该综述纳入的23项临床试验包括1923名患者:治疗组898名,对照组1025名。CBT的缓解率优于眼动脱敏再处理疗法(EMDR)(RR = 0.35;95%CI:0.16;0.79;p = 0.01)或支持性疗法(RR = 0.43;95%CI:0.25;0.74;p = 0.002,意向性分析)。在疗效和依从性方面,CBT与暴露疗法(ET)(RR = 0.90;95%CI:0.58;1.40;p = 0.64)和认知疗法(CT)(RR = 1.01;95%CI:0.67;1.51;p = 0.98)相当。

结论

这些发现表明,特定疗法,如CBT、暴露疗法和认知疗法在治疗PTSD方面同样有效,且比支持性技术更有效。

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