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乳腺癌保乳治疗后的切缘状态:多少切缘阴性才足够?

Margin status after breast-conserving treatment of breast cancer: how much free margin is enough?

作者信息

von Smitten Karl

机构信息

Department of GI and General Surgery, Breast Surgery Unit, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

J Surg Oncol. 2008 Dec 15;98(8):585-7. doi: 10.1002/jso.21038.

Abstract

In breast conserving surgery the margins of the specimen have to be tumor free. There is no universal agreement on the width of the tumor free margin. The width has some impact on recurrence rate, and at least 5 mm seems to be preferred and this is especially important in extensive intraductal component. In ductal cancer in situ the free margin should be at least 5 mm, preferably 10 mm. Oncoplastic surgery is beneficial for reaching adequate margins.

摘要

在保乳手术中,标本切缘必须无肿瘤。对于无瘤切缘的宽度尚无普遍共识。切缘宽度对复发率有一定影响,至少5毫米似乎是比较理想的,这在广泛的导管内成分中尤为重要。在导管原位癌中,切缘应至少5毫米,最好为10毫米。整形手术有助于获得足够的切缘。

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