Mpairamidis Evriviadis, Alexiou George A, Stefanaki Kalliopi, Sfakianos George, Prodromou Neofytos
Department of Neurosurgery, Children's Hospital Agia Sofia, Athens, Greece.
J Child Neurol. 2008 Dec;23(12):1481-3. doi: 10.1177/0883073808319316.
Gangliogliomas are usually benign slow-growing neoplasms, seen mainly in the first 3 decades of life and are prevalently located supratentorial, mostly in the temporal and frontal lobe. The authors present a rare case of a brainstem ganglioglioma in an 11-year-old boy who was referred to their hospital complaining of episodes of blurry vision, loss of memory, gait disturbances, and morning headache with vomiting, lasting for over a month. Computed tomography and magnetic resonance imaging scans revealed a mass on the dorsal surface of the brainstem, compressing the brainstem and producing secondary obstructive hydrocephalus. The patient was operated upon, and the histopathology revealed the presence of a ganglioglioma grade II (World Health Organization classification). On follow-up examination after 1 year, a minor gait imbalance was the only finding. A total resection should be always attempted, where possible in brainstem gangliogliomas. Close follow-up is mandatory, and re-resection or radiotherapy should be considered in case of tumor recurrence.
神经节胶质瘤通常是良性的、生长缓慢的肿瘤,主要见于生命的前三十年,且大多位于幕上,主要在颞叶和额叶。作者报告了一例罕见的脑干神经节胶质瘤病例,患者为一名11岁男孩,因视物模糊、记忆力减退、步态障碍以及晨起头痛伴呕吐等症状持续一个多月而转诊至他们的医院。计算机断层扫描和磁共振成像扫描显示脑干背侧有一个肿块,压迫脑干并导致继发性梗阻性脑积水。该患者接受了手术,组织病理学检查显示为二级神经节胶质瘤(世界卫生组织分类)。在术后1年的随访检查中,仅发现轻微的步态不平衡。对于脑干神经节胶质瘤,在可能的情况下应始终尝试进行全切除。密切随访是必要的,若肿瘤复发,则应考虑再次切除或放疗。