Ozdemir Mustafa, Baysal Ibrahim, Engin Burhan, Ozdemir Suna
Department of Dermatology, Meram Medical Faculty, Selçuk University, Konya, Turkey.
Dermatol Surg. 2009 Jan;35(1):92-7. doi: 10.1111/j.1524-4725.2008.34387.x. Epub 2008 Dec 8.
Angiokeratomas are typically asymptomatic, blue-to-red papules with a scaly surface located on the scrotum, shaft of penis, labia majora, inner thigh, or lower abdomen. The treatment of angiokeratomas may be necessary if they bleed and lead to patient anxiety.
To determine the safety and effectiveness of long-pulse 1,064 neodymium-doped yttrium aluminium garnet (Nd:YAG) laser for the treatment of angiokeratomas of Fordyce.
Ten consecutive patients with angiokeratoma of Fordyce were treated with long-pulse Nd:YAG laser in two to six sessions. The three authors independently assessed improvement of the lesion based on digital photographs taken before the treatment and 2 months after the end of the treatment.
Significant (>75%, <100%) and moderate (>50%, <75%) improvement was seen in six and two patients, respectively. Complete improvement was achieved in one patient. Transient swelling, purpura, bleeding, and some pain in the treated area were noted in all patients as short-term side effects. There were no permanent side effects.
The long-pulse Nd:YAG laser is a highly effective and safe treatment for angiokeratoma of Fordyce.
血管角皮瘤通常无症状，表现为蓝色至红色丘疹，表面有鳞屑，位于阴囊、阴茎体、大阴唇、大腿内侧或下腹部。如果血管角皮瘤出血并导致患者焦虑，则可能需要进行治疗。
确定长脉冲掺钕钇铝石榴石（Nd:YAG）激光治疗福代斯血管角皮瘤的安全性和有效性。
连续10例福代斯血管角皮瘤患者接受长脉冲Nd:YAG激光治疗，共进行2至6次治疗。三位作者根据治疗前和治疗结束后2个月拍摄的数码照片，独立评估病变的改善情况。
分别有6例和2例患者病变显著改善（>75%，<100%）和中度改善（>50%，<75%）。1例患者实现完全改善。所有患者均出现治疗区域短暂肿胀、紫癜、出血和一些疼痛等短期副作用，未出现永久性副作用。
长脉冲Nd:YAG激光是治疗福代斯血管角皮瘤的一种高效且安全的方法。
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