沙特阿拉伯消防员的烟雾对某些生化参数的影响。

Effect of fire smoke on some biochemical parameters in firefighters of Saudi Arabia.

机构信息

Biochemistry Department, Faculty of Science, King Abdualziz University, Jeddah, KSA.

出版信息

J Occup Med Toxicol. 2008 Dec 11;3:33. doi: 10.1186/1745-6673-3-33.

DOI:10.1186/1745-6673-3-33

PMID:19077241

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2615434/

Abstract

BACKGROUND

Firefighters who are facing fires, are frequently exposed to hazardous materials including carbon monoxide, hydrogen cyanide, hydrogen chloride, benzene, sulphur dioxide, etc. This study aimed to evaluate some relevant serum biochemical and blood hematological changes in activity involved firefighters in comparison to normal subjects.

SUBJECTS AND METHODS

Two groups of male firefighters volunteered to participate in the study. The first included 28 firefighters from Jeddah, while the second included 21 firefighters from Yanbu, with overall age ranged 20-48 years. An additional group of 23 male non-firefighters volunteered from both cities as normal control subjects, of age range 20-43 years. Blood samples were collected from all volunteer subjects and investigated for some relevant serum biochemical and blood hematological changes.

RESULTS

The results obtained showed that, there were statistically significant differences in liver function, kidney function, serum lipid profile, cortisol, creatine kinase, lactate dehydrogenase, iron and its biologically active derivatives, and blood picture in firefighters as compared with the normal control group. These results indicate that, fire smoke mainly affects serum biochemical and blood hematological parameters. Such results might point out to the need for more health protective and prophylactic measures to avoid such hazardous health effects that might endanger firefighters under their highly drastic working conditions.

CONCLUSION

Besides using of personal protective equipments for firefighters to protect them against exposure to toxic materials of fire smoke, it is recommended that, firefighters must be under continuous medical follow up through a standard timetabled medical laboratory investigations to allow for early detection of any serum biochemical or blood hematological changes that might happen during their active service life and to allow for early treatment whenever necessary.

摘要

背景

消防员在面对火灾时，经常会接触到包括一氧化碳、氰化氢、盐酸、苯、二氧化硫等在内的有害物质。本研究旨在评估参与活动的消防员与正常受试者相比，其血清生化和血液学相关变化。

受试者和方法

两组男性消防员自愿参与研究。第一组包括来自吉达的 28 名消防员，第二组包括来自延布的 21 名消防员，年龄在 20-48 岁之间。来自两个城市的 23 名年龄在 20-43 岁之间的非消防员男性志愿者也加入了正常对照组。从所有志愿者受试者中采集血液样本，并对一些相关的血清生化和血液学变化进行调查。

结果

研究结果表明，与正常对照组相比，消防员的肝功能、肾功能、血清脂质谱、皮质醇、肌酸激酶、乳酸脱氢酶、铁及其生物活性衍生物以及血象均存在统计学上的显著差异。这些结果表明，火灾烟雾主要影响血清生化和血液学参数。这些结果可能表明需要采取更多的健康保护和预防措施，以避免在高度恶劣的工作条件下对消防员造成的这种危险的健康影响。