Kang Byung Kook, Park Nam Seon, Jin Dae Ho, Ahn Tae Hong, Park Min Bom, Lee Key Jo, Han Yoon Ju, Park Hyo Jin
Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea.
Korean J Gastroenterol. 2008 Aug;52(2):106-9.
Brunner's gland adenoma is a rare tumor of duodenum. Patients are usually aymptomatic and most are discovered incidentally during the upper gastrointestinal (GI) series or esophagogastroduodenoscopy. These lesions are most commonly located in the duodenal bulb and clinical manifestations are variable. In symptomatic patients, the most common manifestations are GI hemorrhage and duodenal obstruction. On histologic examination, Brunner's gland adenoma that causes clinical symptoms is composed of hyperplastic Brunner's glands and contains mostly an admixture of glandular, adipose, and muscular tissues. We report a case of large Brunner's gland adenoma causing upper gastrointestinal hemorrhage in a 47-year-old woman which was successfully removed by endoscopic resection without complications such as bleeding or perforation. Microscopically, it was entirely composed of variable Brunner's glands.
布伦纳腺腺瘤是一种罕见的十二指肠肿瘤。患者通常无症状,大多数是在上消化道造影或食管胃十二指肠镜检查时偶然发现的。这些病变最常见于十二指肠球部,临床表现多样。有症状的患者中,最常见的表现是上消化道出血和十二指肠梗阻。组织学检查显示,引起临床症状的布伦纳腺腺瘤由增生的布伦纳腺组成,主要包含腺性、脂肪性和肌肉组织的混合物。我们报告一例47岁女性因大型布伦纳腺腺瘤导致上消化道出血的病例,该病例通过内镜切除成功治愈,未出现出血或穿孔等并发症。显微镜下,它完全由形态各异的布伦纳腺组成。