Liu Lei, Li Jie Shou, Li Ning, Ren Jian An, Zhao Yun Zhao
Medical School of Nanjing University, Nanjing Jinling Hospital, Research Institute of General Surgery, Nanjing, China.
Surgery. 2009 Jan;145(1):114-9. doi: 10.1016/j.surg.2008.08.014. Epub 2008 Oct 2.
Synthetic mesh can increase the risk of complications if it is placed directly over viscera or if the site is contaminated. Therefore, the use of bioprosthetic materials has increased rapidly. Neither synthetic nor bioprosthetic mesh is ideal for reconstructing infected complex abdominal wall defects. Our method using an autogenous pedicled demucosalized small intestinal sheet may be an alternative.
Forty-one patients with infected, complex abdominal wall defects, with a mean defect size of 108 cm(2), underwent abdominal wall reconstruction using an autogenous, pedicled, demucosalized small intestinal sheet between January 1970 and December 2006. All patients had bowel and enterocutaneous fistulae in the defect. During operation, after resecting fistulae, the mucosa of the longitudinally split small intestine was scraped off with a scalpel to obtain an autogenous, pedicled, demucosalized small intestinal sheet, and then used to bridge the defect in the abdominal wall. A split thickness skin graft was then applied directly onto the demucosalized surface of the split bowel.
The operative procedure was successful in patients. The wounds between the intestinal sheets and abdominal walls healed spontaneously. Four patients developed regeneration of intestinal mucosa in some of the "meshed" skin grafts at 4-5 days postoperatively. The follow-up evaluation was 24 months to 20 years. Abdominal wall herniation, fistula formation, or bowel obstruction did not occur in these patients.
Autogenous, pedicled, demucosalized small intestinal sheets can be an effective method for reconstructing infected complex abdominal wall defects.
如果将合成网片直接放置在内脏上方或放置部位受到污染,会增加并发症的风险。因此,生物假体材料的使用迅速增加。合成网片和生物假体网片都不是重建感染性复杂腹壁缺损的理想材料。我们使用自体带蒂去黏膜小肠片的方法可能是一种替代方案。
1970年1月至2006年12月期间,41例感染性复杂腹壁缺损患者接受了腹壁重建,平均缺损面积为108平方厘米,采用自体带蒂去黏膜小肠片进行修复。所有患者的缺损处均有肠管和肠皮肤瘘。手术过程中,切除瘘管后,用手术刀刮除纵向切开的小肠黏膜,获取自体带蒂去黏膜小肠片,然后用于修补腹壁缺损。然后将分层皮片直接覆盖在切开肠管的去黏膜表面。
手术对患者均获成功。小肠片与腹壁之间的伤口自行愈合。4例患者在术后4至5天,部分“网状”皮片处出现肠黏膜再生。随访时间为24个月至20年。这些患者未发生腹壁疝、瘘管形成或肠梗阻。
自体带蒂去黏膜小肠片可作为重建感染性复杂腹壁缺损的有效方法。