Barber Matthew D, Kleeman Steven, Karram Mickey M, Paraiso Marie Fidela R, Ellerkmann Mark, Vasavada Sandip, Walters Mark D
Department of Obstetrics and Gynecology and Glickman Urological Institute, Cleveland Clinic, Cincinnati, OH, USA.
Am J Obstet Gynecol. 2008 Dec;199(6):666.e1-7. doi: 10.1016/j.ajog.2008.07.050.
The objective of the study was to identify predictors of recurrent urinary incontinence (UI) 1 year after treatment with tension-free vaginal tape (TVT) and transobturator tape (TOT).
One hundred sixty-two women with urodynamic stress urinary incontinence (SUI) were included in a clinical trial comparing TVT with TOT with at least 1 year of follow-up were included in this analysis. Potential clinical and urodynamic predictors for development of "any recurrent UI" or "recurrent SUI" 1 year after surgery were evaluated using logistic regression models.
Subjects who received concurrent prolapse surgery and those taking anticholinergic medications preoperatively were more likely to develop any recurrent UI. Increasing age was independently associated with recurrent SUI. Risk factors were similar for TVT and TOT for both definitions of treatment failure.
Concurrent prolapse surgery and preoperative anticholinergic medication use are associated with increased risk of developing recurrent UI 1 year after TVT or TOT. Increasing age is specifically associated with the recurrence of SUI symptoms.
本研究的目的是确定无张力阴道吊带术(TVT)和经闭孔吊带术(TOT)治疗后1年复发性尿失禁(UI)的预测因素。
162例患有尿动力学压力性尿失禁(SUI)的女性被纳入一项比较TVT和TOT的临床试验,本分析纳入了至少随访1年的患者。使用逻辑回归模型评估术后1年发生“任何复发性UI”或“复发性SUI”的潜在临床和尿动力学预测因素。
接受同期脱垂手术的受试者和术前服用抗胆碱能药物的受试者更有可能出现任何复发性UI。年龄增长与复发性SUI独立相关。对于两种治疗失败的定义,TVT和TOT的危险因素相似。
同期脱垂手术和术前使用抗胆碱能药物与TVT或TOT术后1年发生复发性UI的风险增加有关。年龄增长与SUI症状的复发尤其相关。