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自由生活变形虫与皮炎外瓶霉之间的关系:一项初步研究。

Relationships between free living amoebae and Exophiala dermatitidis: a preliminary study.

作者信息

Cateau Estelle, Mergey Tiphaine, Kauffmann-Lacroix Catherine, Rodier Marie-Helene

机构信息

Laboratoire de parasitologie et mycologie médicale, CHU La Milétrie, Poitiers, France.

出版信息

Med Mycol. 2009 Feb;47(1):115-8. doi: 10.1080/13693780802545592. Epub 2008 Dec 12.

DOI:10.1080/13693780802545592
PMID:19085458
Abstract

Free living amoebae can play a role as reservoirs for pathogens isolated from hospital water. We have investigated the potential interactions between two protozoa (Acanthamoeba castellanii and Hartmanella vermiformis) that may be recovered from hospital water tips and Exophiala dermatitidis, a black yeast often recovered from water sources. We showed that the presence of trophozoites or supernatants of culture of H. vermiformis increased fungal growth, whereas the same phenomenon was observed only with the supernatant of A. castellanii cultures. These preliminary results highlight the fact that the recovering of free-living amoebae in hospital water taps could lead to the development of fungal nosocomial pathogens.

摘要

自由生活阿米巴可作为医院水源中分离出的病原体的储存宿主。我们研究了两种可能从医院水龙头中检出的原生动物(卡氏棘阿米巴和蠕虫状哈特曼阿米巴)与皮炎外瓶霉(一种常从水源中分离出的黑色酵母菌)之间的潜在相互作用。我们发现,蠕虫状哈特曼阿米巴滋养体或培养上清液的存在会促进真菌生长,而同样的现象仅在卡氏棘阿米巴培养上清液中观察到。这些初步结果凸显了医院水龙头中检出自由生活阿米巴可能导致真菌性医院感染病原体滋生这一事实。

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