Pavone Luigi Michele, Tafuri Simona, Avallone Luigi, Staiano Norma, Vittoria Alfredo
Department of Biological Structures, Functions and Technologies, University of Naples Federico II, Via F. Delpino n. 1, Naples, Italy.
Anat Rec (Hoboken). 2009 Feb;292(2):202-6. doi: 10.1002/ar.20833.
The hypothalamic peptide orexin A (oxA) binds specifically the G-protein-coupled orexin receptor 1 (ox1R). It is involved in many physiological functions including the regulation of food intake, sleep-wake cycle, arterial blood pressure, heart rate, and sexual behavior. The localization of oxA in adrenal glands, stomach, bowel, pancreas, and testis has recently been assessed. Here, we provide the first evidence for the expression of oxA and ox1R in the vestibular glands of mammalian genital tract.
下丘脑肽食欲素A（oxA）特异性结合G蛋白偶联的食欲素受体1（ox1R）。它参与多种生理功能，包括食物摄入调节、睡眠-觉醒周期、动脉血压、心率和性行为。最近已评估了oxA在肾上腺、胃、肠、胰腺和睾丸中的定位。在此，我们首次提供了oxA和ox1R在哺乳动物生殖道前庭腺中表达的证据。
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