Ratan Simmi K, Ratan John, Rattan Kamal Nain
PGIMS, Rohtak, Haryana, India.
Pediatr Surg Int. 2009 Feb;25(2):185-90. doi: 10.1007/s00383-008-2312-8. Epub 2008 Dec 19.
Trial of a new procedure of hypospadias repair based on the incorporation of the entire available innate urethral tissue for the formation of neo-urethra in patients with hypospadias.
Fifteen consecutive children, nine with distal hypospadias and six with proximal hypospadias (all with severe chordee), whose parents consented to application of a new procedure of hypospadias repair, were the study subjects. This procedure is inspired by Cantwell Ransley procedure for epispadias repair and Snodgras procedure for hypospadias repair. The entire urethral plate was mobilized (i.e., lifted off the corpora) distal to the urethral meatus and was tubularized in two layers; inner urethral skin and outer spongiosal tissue, in Duplay fashion. The repair was reinforced with dartos vascularized flap. The skin incisions on the urethral strip are guided by the disposition of the spongiosal tissue underlying the urethral plate (rather than the conventional U-shaped incision on either side of hypospadiac urethral meatus). In the patients with proximal hypospadias with severe chordee urethral advancement was combined to achieve orthoplasty and a single stage hypospadias repair. The catheter was removed on tenth postoperative day.
Even in patients with proximal hypospadias with severe chordee, good single staged repair was achieved without resorting to dorsal plication that would have been necessary had any other methods based on the preservation of urethral plate was performed in these subjects. Therefore, the procedure was found to have an extended applicability to even those patients where tubularized incised urethral plate urethroplsty is not advised. All patients had good results (in 1 year follow-up), except in three early subjects of the series; two of whom developed minor urethrocutaneous fistulae (probably due to frank urinary leak secondary to repeated catheter blockade) and one developed partial glanular wound dehiscence.
Though the authors have an initial limited experience with this procedure, the procedure is likely to have a promising future due to its versatility and utilization of the entire urethral tissue.
基于纳入全部可用的先天性尿道组织来为尿道下裂患者构建新尿道,对一种新的尿道下裂修复手术进行试验。
连续纳入15名儿童,其中9名患有远端尿道下裂,6名患有近端尿道下裂(均伴有严重阴茎下弯),其父母同意采用一种新的尿道下裂修复手术,作为研究对象。该手术灵感来源于坎特韦尔·兰斯利法治疗膀胱外翻修复术以及斯诺德格拉斯法治疗尿道下裂修复术。在尿道口远端将整个尿道板游离(即从阴茎海绵体上掀起),并分两层管状化;内层为尿道皮肤,外层为海绵体组织,采用杜普雷方式。用带蒂肉膜血管化皮瓣加强修复。尿道条上的皮肤切口根据尿道板下方海绵体组织的分布来引导(而非传统的在尿道下裂尿道口两侧做U形切口)。对于伴有严重阴茎下弯的近端尿道下裂患者,联合尿道前移以实现阴茎伸直并进行一期尿道下裂修复。术后第10天拔除导尿管。
即使是伴有严重阴茎下弯的近端尿道下裂患者,也实现了良好的一期修复,无需采用在这些患者中若采用基于保留尿道板的任何其他方法时原本所需进行的阴茎背侧折叠术。因此发现该手术甚至对那些不建议行管状切开尿道板尿道成形术的患者也具有广泛的适用性。所有患者(1年随访期内)均取得良好效果,但该系列早期病例中有3例除外;其中2例出现轻微尿道皮肤瘘(可能是由于反复导尿管堵塞继发明显尿漏所致),1例出现部分龟头伤口裂开。
尽管作者对该手术最初经验有限,但由于其多功能性以及对整个尿道组织的利用,该手术可能具有广阔前景。