El Hage Rawad Philippe, Courteix Daniel, Benhamou Claude-Laurent, Jacob Christophe, Jaffré Christelle
UMR-S658, CHR d'Orléans, CHR d'Orléans-Porte Madeleine, BP 2439, 45032, Orléans Cedex 1, France,
Eur J Appl Physiol. 2009 Mar;105(5):759-64. doi: 10.1007/s00421-008-0959-4. Epub 2008 Dec 19.
The aim of this study was to determine the relative importance of lean mass (LM) and fat mass (FM) on bone mineral density (BMD) in a group of adolescent girls and boys. A total of 65 adolescent boys and 35 adolescent girls participated in this study. Whole body (WB) and lumbar spine (L1-L4) BMD were measured by dual-energy X-ray absorptiometry (DXA). Body composition was assessed using the same technique. In boys, LM was strongly related to WBBMD (r = 0.68; p < 0.001) and to L1-L4 BMD (r = 0.61; p < 0.001), whereas FM was not positively related to BMD and was negatively associated with WB bone mineral apparent density (WBBMAD). In girls, both LM and FM were positively related to WBBMD (r = 0.41; p < 0.05 and r = 0.49; p < 0.01, respectively), whereas only FM was correlated to L1-L4 BMD (r = 0.33; p < 0.05). Finally, in a multiple regression analysis, FM was found to be a better positive determinant of WBBMD than LM in girls, whereas in boys, FM was found to be a negative determinant of WBBMD and L1-L4 BMD. This study suggests that LM is a strong determinant of WBBMD and L1-L4 BMD in boys, and that FM is a stronger determinant of WBBMD than LM in girls.
本研究的目的是确定在一组青春期女孩和男孩中，瘦体重（LM）和脂肪量（FM）对骨密度（BMD）的相对重要性。共有65名青春期男孩和35名青春期女孩参与了本研究。采用双能X线吸收法（DXA）测量全身（WB）和腰椎（L1-L4）的骨密度。使用相同技术评估身体成分。在男孩中，瘦体重与全身骨密度（r = 0.68；p < 0.001）和L1-L4骨密度（r = 0.61；p < 0.001）密切相关，而脂肪量与骨密度无正相关，且与全身骨矿物质表观密度（WBBMAD）呈负相关。在女孩中，瘦体重和脂肪量均与全身骨密度呈正相关（分别为r = 0.41；p < 0.05和r = 0.49；p < 0.01），而只有脂肪量与L1-L4骨密度相关（r = 0.33；p < 0.05）。最后，在多元回归分析中，发现脂肪量在女孩中是全身骨密度比瘦体重更好的正向决定因素，而在男孩中，脂肪量是全身骨密度和L1-L4骨密度的负向决定因素。本研究表明，瘦体重是男孩全身骨密度和L1-L4骨密度的重要决定因素，而在女孩中，脂肪量是全身骨密度比瘦体重更强的决定因素。
