通过介电谱分析人指甲板中的分子相互作用。
Molecular interactions in human nail plate analysed by dielectric spectroscopy.
作者信息
Marzec E, Olszewski J
机构信息
Department of Biophysics, Poznań University of Medical Sciences, Fredry 10, 61-701 Poznań, Poland.
出版信息
Colloids Surf B Biointerfaces. 2009 Feb 15;69(1):91-4. doi: 10.1016/j.colsurfb.2008.11.003. Epub 2008 Nov 17.
The influence of diabetes mellitus on dielectric properties of the human fingernail was measured in vitro in the alpha-dispersion region. The frequency dependencies of the permittivity and conductivity for the healthy and the diabetic nail plate revealed three separate relaxations, which were similar for both materials. Significant differences were observed in the values of permittivity at the same frequency between the healthy and the diabetic nails with low water content of about 0% and 3%. Results of this paper suggest that hyperglycemia alters the first-order structure of the nail keratin macromolecule.
在体外α-色散区域测量了糖尿病对人指甲介电特性的影响。健康指甲和糖尿病患者指甲板的介电常数和电导率的频率依赖性显示出三种不同的弛豫，两种材料的弛豫相似。在含水量约为0%和3%的健康指甲和糖尿病指甲之间，在相同频率下的介电常数数值上观察到显著差异。本文结果表明，高血糖会改变指甲角蛋白大分子的一级结构。
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