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急性心肌梗死患者中糖尿病的患病率及其影响:一项 10 年经验。

Prevalence and impact of diabetes mellitus in patients with acute myocardial infarction: a 10-year experience.

机构信息

Department of Cardiology and Cardiothoracic Surgery, Hamad Medical Corporation, Doha, Qatar.

出版信息

Angiology. 2009;60(6):683-8. doi: 10.1177/0003319708328568. Epub 2008 Dec 18.

Abstract

BACKGROUND

Diabetes mellitus is associated with a higher incidence of acute myocardial infarction.

OBJECTIVE

To study the prevalence and outcome of patients with diabetes among patients with acute myocardial infarction.

METHODS

Retrospectively, patients who presented with acute myocardial infarction in a 10-year period were identified from the coronary care unit database.

RESULTS

A total of 1598 Qatari patients were admitted with acute myocardial infarction, 863 (54%) of them had diabetes mellitus (females 68.5% vs males 48.3%; P < .001). In-hospital mortality rate was non-significantly higher in diabetic patients (18% vs 15% P = .15). Aspirin (odds ratio 2.39, 95% confidence interval 1.96-2.90, P = .003] and beta-blocker use (odds ratio 1.75, 95% CI 1.21-2.52, P = .0001) were independently associated with reduced mortality risk.

CONCLUSIONS

The prevalence of diabetes mellitus among patients with acute myocardial infarction in a geographically defined population in the developing world is high with a trend for poor outcomes. However, mortality was not significantly higher in diabetes mellitus than non-diabetes mellitus patients.

摘要

背景

糖尿病与急性心肌梗死的发病率升高有关。

目的

研究急性心肌梗死患者中糖尿病患者的患病率和结局。

方法

从冠心病监护病房数据库中回顾性地确定了在 10 年期间出现急性心肌梗死的患者。

结果

共有 1598 名卡塔尔患者因急性心肌梗死住院,其中 863 名(54%)患有糖尿病(女性占 68.5%,男性占 48.3%;P<.001)。糖尿病患者的住院死亡率非显著更高(18%比 15%,P=0.15)。阿司匹林(优势比 2.39,95%置信区间 1.96-2.90,P=0.003]和β-受体阻滞剂的使用(优势比 1.75,95%置信区间 1.21-2.52,P=0.0001)与降低死亡率风险独立相关。

结论

在发展中国家一个地理上确定的人群中,急性心肌梗死患者中糖尿病的患病率较高,且预后较差。然而,糖尿病患者的死亡率并未显著高于非糖尿病患者。

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