Arisaka Hirofumi, Sakuraba Shigeki, Kobayashi Reiko, Kitahama Homare, Nishida Naofumi, Furuya Munetaka, Yoshida Kazu-ichi
Division of Anesthesiology, Department of Clinical Care Medicine, Kanagawa Dental College, Kanagawa, Japan.
Anesth Prog. 2008 Winter;55(4):121-3. doi: 10.2344/0003-3006-55.4.121.
The high risks associated with general anesthesia in obstructive sleep apnea syndrome (OSAS) patients have been reported. Many authors have suggested that the intraoperative administration of opioids and sedatives should be limited or avoided because these drugs selectively impair muscle activity in the upper airway. We report the case of an OSAS patient who was managed with nasal continuous positive airway pressure (NCPAP) and treated safely in spite of the use of conventional anesthetic and analgesic agents typically used for patients without OSAS. She had little pain during the perioperative period. It is suggested that NCPAP is an effective treatment for not only preventing airway obstructive apnea but for allowing the administration of anesthetic and analgesic drugs without major complications.
阻塞性睡眠呼吸暂停综合征（OSAS）患者全身麻醉相关的高风险已见报道。许多作者建议，术中应限制或避免使用阿片类药物和镇静剂，因为这些药物会选择性地损害上呼吸道肌肉活动。我们报告一例OSAS患者，尽管使用了通常用于非OSAS患者的传统麻醉和镇痛药物，但通过鼻持续气道正压通气（NCPAP）进行管理并安全接受了治疗。围手术期她几乎没有疼痛。提示NCPAP不仅是预防气道阻塞性呼吸暂停的有效治疗方法，而且能使麻醉和镇痛药物的使用不发生重大并发症。
