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手辅助腹腔镜根治性膀胱切除术及体外尿液改道:31例经验

Hand-assisted laparoscopic radical cystectomy and extracorporeal urinary diversion: experience with 31 cases.

作者信息

Wang Sheng-zheng, Chen Ling-wu, Chen Wei, Zhang Yong-hai

机构信息

Department of Urology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

出版信息

Int J Urol. 2008 Dec;15(12):1035-8. doi: 10.1111/j.1442-2042.2008.02167.x.

Abstract

OBJECTIVES

To report our techniques and experience with hand-assisted laparoscopic radical cystectomy and extracorporeal urinary diversion for bladder cancer.

METHODS

Between May 2004 and November 2007, 31 patients (mean age 61.3 years, range 40-79) underwent hand-assisted laparoscopic radical cystectomy with extracorporeal urinary diversion for bladder cancer. Five patients had previously undergone abdominal surgeries. Data were collected with respect to patient demographics, perioperative outcomes and short-term oncological follow up.

RESULTS

Twenty-four patients underwent an ileal conduit and seven patients underwent an orthotopic neobladder. Mean operative time was 365.7 min (range 245 to 530). Estimated blood loss was 250.9 cc (range 100 to 500), with a transfusion rate of 9.7%. Oral liquids were resumed at 4.3 days and the mean hospital stay was 19.7 days. There were no intraoperative complications. Postoperative early complications (within 30 days of surgery) occurred in six patients (19.4%). Two wound infections, one urinary leak, one wound dehiscence, one bowel obstruction and one alimentary tract hemorrhage were all treated conservatively. Late complications occurred in three patients (two parastomal hernias and one ureteroenteric stricture). With a mean follow up of 18 months, 27 patients had no evidence of disease. One patient died because of cancer and one died for unrelated causes. One was alive with local recurrences and one with lung metastasis.

CONCLUSIONS

Hand-assisted laparoscopic radical cystectomy is a safe, reproducible and minimally invasive option for bladder cancer patients.

摘要

目的

报告我们在膀胱癌手辅助腹腔镜根治性膀胱切除术及体外尿流改道方面的技术和经验。

方法

2004年5月至2007年11月期间,31例患者(平均年龄61.3岁,范围40 - 79岁)接受了手辅助腹腔镜根治性膀胱切除术及体外尿流改道治疗膀胱癌。5例患者既往有腹部手术史。收集了患者人口统计学、围手术期结果及短期肿瘤学随访的数据。

结果

24例患者行回肠膀胱术,7例患者行原位新膀胱术。平均手术时间为365.7分钟(范围245至530分钟)。估计失血量为250.9毫升(范围100至500毫升),输血率为9.7%。术后4.3天恢复口服液体,平均住院时间为19.7天。无术中并发症。术后早期并发症(术后30天内)发生在6例患者(19.4%)中。2例伤口感染、1例尿漏、1例伤口裂开、1例肠梗阻和1例消化道出血均经保守治疗。晚期并发症发生在3例患者中(2例造口旁疝和1例输尿管肠吻合口狭窄)。平均随访18个月,27例患者无疾病证据。1例患者因癌症死亡,1例因无关原因死亡。1例患者存活但有局部复发,1例有肺转移。

结论

手辅助腹腔镜根治性膀胱切除术对于膀胱癌患者是一种安全、可重复且微创的选择。

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