Marchertiene Irena Agniete, Macas Andrius, Karbonskiene Aurika
Department of Anesthesiology, Kaunas University of Medicine, Eiveniu 2, Kaunas.
Medicina (Kaunas). 2008;44(11):871-6.
Airway obstruction is a quite common complication while its conditioned pulmonary edema--rare. Causes associated with anesthesia are various. Forced inspiratory efforts against an obstructed upper airway generate peak negative intrathoracic pressure. This may cause pulmonary edema and in some cases pulmonary hemorrhage. Last-mentioned is extremely rare. Pulmonary edema may arise soon after airway obstruction as well as later, after some hours. Damage of bronchi is found seldom during bronchoscopy in case of pulmonary hemorrhage, while more often alveolar damage is observed due to alveolar membrane damage. Hemorrhage is conditioned by hydrostatic pressure level, level of hypoxia, damage to bronchi or alveoli (disruption of alveolar membrane). Early diagnosis of negative-pressure pulmonary edema or pulmonary hemorrhage is very important, because this affects postoperative morbidity and mortality of the patients. Two cases of pulmonary edema and hemorrhage after upper airway obstruction as well as literature overview are presented in this article. Pulmonary hemorrhage developed during anesthesia with ketamine, conditioned by increment of hydrostatic pressure, hypoxia, and effects of ketamine on hemodynamics.
气道梗阻是一种相当常见的并发症,而其导致的肺水肿则较为罕见。与麻醉相关的原因多种多样。对抗阻塞的上气道进行用力吸气会产生胸内负压峰值。这可能会导致肺水肿,在某些情况下还会导致肺出血。后者极为罕见。肺水肿可能在气道梗阻后很快出现,也可能在数小时后的较晚时间出现。在肺出血的情况下,支气管镜检查很少发现支气管损伤,而由于肺泡膜损伤,更常观察到肺泡损伤。出血取决于静水压水平、缺氧程度、支气管或肺泡的损伤(肺泡膜破裂)。负压性肺水肿或肺出血的早期诊断非常重要,因为这会影响患者的术后发病率和死亡率。本文介绍了两例上气道梗阻后发生肺水肿和出血的病例以及文献综述。肺出血发生在氯胺酮麻醉期间,由静水压升高、缺氧以及氯胺酮对血流动力学的影响所致。