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老年患者的胸外科手术——合并症是限制因素。

Thoracic surgery in the elderly--co-morbidity is the limit.

作者信息

Limmer Stefan, Hauenschild Lena, Eckmann Christian, Czymek Ralf, Schmidt Henriette, Bruch Hans-Peter, Kujath Peter

机构信息

Department of Surgery, University Hospital of Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.

出版信息

Interact Cardiovasc Thorac Surg. 2009 Apr;8(4):412-6. doi: 10.1510/icvts.2008.191346. Epub 2009 Jan 9.

Abstract

A retrospective chart review was performed in 242 consecutive patients aged 65 years or older who were treated in an academic surgical centre between January 2004 and July 2007. A total of 249 thoracic procedures were performed in 242 patients, of whom 143 were men and 99 women with a mean age of 69.9 years (range 65-92). Overall operative mortality was 2.4%, rising to 26.4% in emergency patients. Negative predictors for perioperative mortality were: American Society of Anesthesiology (ASA) class 4, pre-existing kidney failure, leucocytosis, low haemoglobin, elevated C-reactive protein, diabetes mellitus and emergency surgery. In addition, the risk of major and minor complications resulting in a prolonged hospital stay was increased in emergency patients, patients with multiple co-morbidities and ASA class 3 or 4. Appropriate thoracic surgery can be offered to the elderly with an acceptable level of perioperative morbidity and mortality. Regardless of age, a high degree of co-morbidity or emergency surgery are the main risk factors for perioperative mortality and/or prolonged hospital stay.

摘要

对2004年1月至2007年7月间在一家学术性外科中心接受治疗的242例65岁及以上的连续患者进行了回顾性病历审查。242例患者共进行了249例胸部手术,其中男性143例,女性99例,平均年龄69.9岁(范围65 - 92岁)。总体手术死亡率为2.4%,急诊患者中升至26.4%。围手术期死亡的负性预测因素为:美国麻醉医师协会(ASA)4级、既往肾衰竭、白细胞增多、血红蛋白低、C反应蛋白升高、糖尿病和急诊手术。此外,急诊患者、患有多种合并症的患者以及ASA 3级或4级患者发生导致住院时间延长的严重和轻微并发症的风险增加。可以为老年人提供合适的胸外科手术,其围手术期发病率和死亡率处于可接受水平。无论年龄如何,高度合并症或急诊手术是围手术期死亡和/或住院时间延长的主要危险因素。

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