2,3-二氧代-5-（取代）-芳基吡咯及其2-氧代-5-芳基-3-腙基吡咯烷衍生物的合成
Synthesis of 2,3-dioxo-5-(substituted)-arylpyrroles and their 2-oxo-5-aryl-3-hydrazone pyrrolidine derivatives.
作者信息
Mohammat M F, Shaameri Z, Hamzah A S
机构信息
Organic Synthesis Laboratory, Institute of Science, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia.
出版信息
Molecules. 2009 Jan 7;14(1):250-6. doi: 10.3390/molecules14010250.
Abstract
Some novel 2,3-dioxo-5-(substituted)-arylpyrroles have been synthesized. Among these, pyrrolidine compound 1b was converted to 2,3-dioxo-5-aryl pyrrolidine 2b. Finally a set of hydrazone derivatives was obtained from the reaction of 2b with various hydrazine salts. The structures of all the new synthesized compounds were confirmed by elemental analyses, IR and 1H-NMR spectra.
摘要
已经合成了一些新型的2,3-二氧代-5-（取代）-芳基吡咯。其中，吡咯烷化合物1b被转化为2,3-二氧代-5-芳基吡咯烷2b。最后，通过2b与各种肼盐的反应得到了一组腙衍生物。所有新合成化合物的结构通过元素分析、红外光谱和1H-NMR光谱得以确证。
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