[泪液酶在肝下胆汁淤积性梗阻性黄疸诊断中的分析]
[Analysis of tear enzymes in the diagnosis of obstructive jaundice associated with subhepatic cholestasis].
作者信息
Terekhina N A, Zarivchatskiĭ M F, Soldatenko N V
出版信息
Klin Lab Diagn. 2008 Nov(11):13-5.
The activity of enzymes, such as alkaline phosphatase, gamma-glutamyl transpeptidase, and leicine aminopeptidase, was found to be increased in the serum and tear of 28 patients with obstructive jaundice. In malignant tumor-induced jaundice, the activity of the enzymes, the indicators of cholestasis, was higher than that in obstructive jaundice caused by extrahepatic bile duct calculi. A new method has been devised for noninvasive diagnosis of obstructive jaundice from tear enzyme immunoassay. The method is simple, reliable, and usable at a clinical laboratory.
研究发现，28例梗阻性黄疸患者的血清和泪液中，碱性磷酸酶、γ-谷氨酰转肽酶和亮氨酸氨肽酶等酶的活性升高。在恶性肿瘤所致黄疸中，作为胆汁淤积指标的这些酶的活性高于肝外胆管结石所致梗阻性黄疸。现已设计出一种通过泪液酶免疫测定对梗阻性黄疸进行无创诊断的新方法。该方法简便、可靠，可在临床实验室使用。
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