Li L Y, Zhao Q X, Luo W C
Peking Union Medical College Hospital, Beijing.
Zhonghua Nei Ke Za Zhi. 1991 Jun;30(6):347-9, 382.
Thirty patients diagnosed as chylothorax and chyloperitoneum (13 of chylothorax, 9 of chyloperitoneum and 8 of both) in PUMC Hospital from 1923 to 1989 were reported. Thus, the incidence rate of these two diseases is rather low. The commonest causes were iatrogenic trauma (9 cases) and malignant tumor (7 cases). Other causes were tuberculosis (5 cases), lymphangioma (2 cases), Behcet's syndrome (1 case) and non-iatrogenic trauma (1 case). The etiology was not known in 5 cases. Acute episode was observed in patients with traumatic chylous effusion; it was usually manifested as dyspnea or abdominal distention. Patients with nontraumatic chylous effusion usually run a chronic course. The characteristics of chylous effusion were analyzed. Lymphangiography and lymphoscintigraphy with 99m TC-labeled dextran play important roles in diagnosis and treatment. It has been suggested that the changes in T-cell immunocompetence is important in determining whether the treatment should be conservative or operative. If chylous effusion is due to tuberculosis, antituberculosis treatment should be instituted.
本文报告了1923年至1989年期间在北京协和医院确诊为乳糜胸和乳糜腹的30例患者(其中乳糜胸13例,乳糜腹9例,两者均有的8例)。因此,这两种疾病的发病率相当低。最常见的病因是医源性创伤(9例)和恶性肿瘤(7例)。其他病因包括结核病(5例)、淋巴管瘤(2例)、白塞病(1例)和非医源性创伤(1例)。5例病因不明。外伤性乳糜性积液患者可出现急性发作,通常表现为呼吸困难或腹胀。非外伤性乳糜性积液患者通常病程呈慢性。分析了乳糜性积液的特点。淋巴管造影和用99m锝标记右旋糖酐的淋巴闪烁造影在诊断和治疗中起重要作用。有人提出,T细胞免疫能力的变化对于决定治疗应采取保守还是手术方式很重要。如果乳糜性积液是由结核病引起的,应进行抗结核治疗。