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先天性心脏病患儿髂股静脉、上下腔静脉狭窄或闭塞的支架置入术:急性结果及中期随访

Stenting of stenotic or occluded iliofemoral veins, superior and inferior vena cavae in children with congenital heart disease: acute results and intermediate follow up.

作者信息

Frazer Jeffrey R, Ing Frank F

机构信息

Rady Children's Hospital, San Diego, CA, USA.

出版信息

Catheter Cardiovasc Interv. 2009 Feb 1;73(2):181-8. doi: 10.1002/ccd.21790.

Abstract

OBJECTIVES

To determine the short and intermediate term outcome following systemic venous stent placement in children with congenital heart disease.

BACKGROUND

Patients with congenital heart disease are at risk of stenosis or occlusion of systemic veins following indwelling lines or catheterizations. Stent dilation may ameliorate symptoms and open the vessel for use during future procedures. We report our acute and intermediate results.

METHODS

All patients with systemic venous stent placement in the iliofemoral veins, inferior or superior vena cava at our institution between 1998 and 2006 were included. Initial and the follow-up catheterization data were reviewed retrospectively.

RESULTS

70 stents were placed in 33 patients (36 vessels). Median age was 2.6 years (0.2-14.2) and weight 11.5 kg (3.8-78.7). 17/36 vessels (47%) were occluded requiring recanalization. Following stent delivery, the mean minimum vessel diameter increased from 3.1 +/- 3.2 to 7.2 +/- 3.0 mm (P < 0.001). There were no major complications. Seventeen patients and vessels had a total of 62 follow-up catheterizations, with median length of follow-up 4.1 years (0.7-9.3). During intermediate follow up, 7/17 vessels (41%) required additional intervention. Six patients had additional balloon dilation of existing stents, and one additional stent was placed. Vessels were further dilated to 8.4 +/- 3.5 mm at the last catheterization.

CONCLUSION

Systemic venous stents are safe and effective in recanalizing stenosed or occluded vessels. At follow-up, reocclusion can occur, however, previously placed stents can be safely recanalized if necessary. Future studies will determine if stenting is indicated in a broader population.

摘要

目的

确定先天性心脏病患儿行体静脉支架置入术后的短期和中期结果。

背景

先天性心脏病患者在留置导管或进行导管插入术后有体静脉狭窄或闭塞的风险。支架扩张可改善症状并使血管开放以便未来手术时使用。我们报告我们的急性和中期结果。

方法

纳入1998年至2006年间在我院接受髂股静脉、下腔静脉或上腔静脉体静脉支架置入术的所有患者。回顾性分析初始及随访时的导管检查数据。

结果

33例患者(36条血管)置入了70枚支架。中位年龄为2.6岁(0.2 - 14.2岁),体重11.5千克(3.8 - 78.7千克)。36条血管中有17条(47%)闭塞,需要再通。支架置入后,平均最小血管直径从3.1±3.2毫米增加到7.2±3.0毫米(P < 0.001)。无重大并发症。17例患者及血管共进行了62次随访导管检查,中位随访时间为4.1年(0.7 - 9.3年)。在中期随访期间,17条血管中有7条(41%)需要额外干预。6例患者对现有支架进行了额外的球囊扩张,另置入了1枚支架。在最后一次导管检查时,血管进一步扩张至8.4±3.5毫米。

结论

体静脉支架在使狭窄或闭塞血管再通方面安全有效。随访时可能会再次闭塞,然而,如有必要,先前置入的支架可安全地再通。未来研究将确定在更广泛人群中是否适合进行支架置入术。

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