Department of Structural and Functional Biology, University of Naples Federico II, Via Cintia, Napoli 80126, Italy.
Biopolymers. 2009 Dec;91(12):989-94. doi: 10.1002/bip.21145.
In my long RNase-life-time I have had the fortune to entertain with Lelio Mazzarella what I have called special interactions, which not only advanced my knowledge of proteins but also gave pleasure, as one obtains by reading a beautiful book, an inspiring poem, or watching a very good movie. In this article, I recall the more than 30-year long story of these interactions in which "it took two," a structural biologist with his coworkers and a biochemist with his coworkers, to flirt with an unusual, dimeric RNase.
在我漫长的 RNase 生涯中,我有幸与 Lelio Mazzarella 一起探讨我所谓的特殊相互作用,这些相互作用不仅提高了我对蛋白质的认识,还像阅读一本美丽的书、一首鼓舞人心的诗或观看一部非常好的电影一样给人带来乐趣。在本文中,我回顾了这些相互作用超过 30 年的历史,其中“需要两个人”,一位结构生物学家和他的同事,以及一位生物化学家和他的同事,一起研究一种不寻常的二聚体 RNase。