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[甲烷营养菌和甲烷单加氧酶的研究进展]

[Research progresses of methanotrophs and methane monooxygenases].

作者信息

Han Bing, Su Tao, Li Xin, Xing Xinhui

机构信息

Institute of Biochemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2008 Sep;24(9):1511-9.

Abstract

Methanotrophs are a group of bacteria capable of utilizing methane as the sole carbon and energy source for their anabolism and catabolism. Since methanotrophs contain the unique enzymes of methane monooxygenases (MMOs), which can catalyze the oxidation of methane and short-chain alkanes and alkenes, they have potential applications in carbon recycle of nature and industrial biotechnology. Therefore, methanotrophs have been paid much more attention by the researchers in recent 20 years. In this paper, the latest progresses in studies of methanotrophs and MMOs were reviewed, including taxonomy, function and distribution of methanotrophs, and structure, function and genetic engineering of MMOs. The future research directions of methanotrophs and MMOs as well as their applications were also discussed.

摘要

甲烷营养菌是一类能够利用甲烷作为其合成代谢和分解代谢的唯一碳源和能源的细菌。由于甲烷营养菌含有独特的甲烷单加氧酶(MMOs),该酶可催化甲烷以及短链烷烃和烯烃的氧化,因此它们在自然界的碳循环和工业生物技术中具有潜在应用。因此,在最近20年里,甲烷营养菌受到了研究人员更多的关注。本文综述了甲烷营养菌和MMOs研究的最新进展,包括甲烷营养菌的分类学、功能和分布,以及MMOs的结构、功能和基因工程。还讨论了甲烷营养菌和MMOs未来的研究方向及其应用。

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