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汇聚微纳生物技术迈向集成生物医学系统:欧盟信息与通信技术计划下的现状与未来展望

Converging micro-nano-bio technologies towards integrated biomedical systems: state of the art and future perspectives under the EU-information & communication technologies program.

作者信息

Lymberis A

机构信息

European Commission, Information Society and Media Directorate-General, Brussels, Belgium.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:6-8. doi: 10.1109/IEMBS.2008.4649076.

Abstract

Research and development at the convergence of microelectronics, nano-materials, biochemistry, measurement technology and information technology is leading to a new class of biomedical systems and applications e.g. molecular imaging, point of care testing, gene therapy and bionics (including on and inside the body sensors and other miniaturised smart systems) which are expected to revolutionise the healthcare provision and quality of life. In particular they are expected to identify diseases at the earliest possible stage, intervene before symptomatic disease becomes apparent and monitor both the progress of the diseases and the effect of intervention and therapeutic procedures. The group of EC-funded projects on Micro-Nano-Bio Convergence Systems, "so-called" MNBS, is made by projects developing systems that use a vast array of technologies to integrate across traditional boundaries between the micro-nano-bio, and info worlds, enabling a wide range of applications from health care to food quality monitoring. It includes mainly two sub-groups, one dealing with systems for in vitro molecular diagnosis and biological/biochemical analysis and the other is dealing with systems for in vivo interaction with the human body. Current status of development and future challenges, technological and socioeconomic, are briefly presented in this paper as background introductory information to the mini-symposium on MNBS. Relevant examples of R&D within the group will be presented in the mini-symposium.

摘要

微电子学、纳米材料、生物化学、测量技术和信息技术交叉领域的研发工作正催生出一类新型生物医学系统及应用,例如分子成像、即时检测、基因治疗和仿生学(包括体内外传感器及其他小型智能系统),这些有望给医疗保健服务和生活质量带来变革。特别是,它们有望在尽可能早的阶段识别疾病,在症状性疾病显现之前进行干预,并监测疾病进展以及干预和治疗程序的效果。欧盟资助的“微纳生物融合系统”(即所谓的MNBS)项目组,由开发利用大量技术跨越微纳生物与信息世界之间传统界限进行整合的系统的项目组成,从而实现从医疗保健到食品质量监测等广泛应用。它主要包括两个子组,一个处理体外分子诊断及生物/生化分析系统,另一个处理与人体进行体内相互作用的系统。本文简要介绍了该领域的发展现状以及未来在技术和社会经济方面面临的挑战,作为MNBS小型研讨会的背景介绍信息。该项目组内相关的研发实例将在小型研讨会上展示。

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