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Model Predictive Control of blood glucose in Type 1 diabetes: the Principal Dynamic Modes approach.

作者信息

Markakis Mihalis G, Mitsis Georgios D, Papavassilopoulos George P, Marmarelis Vasilis Z

机构信息

Electrical Engineering&Computer Science Department, Massachusetts Institute of Technology, USA.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:5466-9. doi: 10.1109/IEMBS.2008.4650451.

DOI:10.1109/IEMBS.2008.4650451
PMID:19163954
Abstract

This computational study demonstrates the efficacy of regulating blood glucose in Type 1 diabetics with a Model Predictive Control strategy, utilizing a nonparametric / Principal Dynamic Modes model. For this purpose, a stochastic glucose disturbance signal is introduced and a simple methodology for predicting its future values is developed. The results of our simulations confirm that the proposed algorithm achieves very good performance, is computationally efficient and avoids hypoglycaemic events.

摘要

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