Takeshima N, Miyakawa H, Okuda K, Hattori S, Hagiwara S, Takatani J, Noguchi T
Oita University Faculty of Medicine, Department of Anesthesiology and Intensive Care Medicine, 1-1 Idaigaoka, Hasama, Oita 879-5593, Japan.
Br J Anaesth. 2009 Mar;102(3):400-7. doi: 10.1093/bja/aen383. Epub 2009 Jan 21.
No data for patients with failed back surgery syndrome (FBSS) based on the location of adhesions separated by epiduroscopic adhesiolysis have been reported.
We performed epiduroscopic adhesiolysis on 28 FBSS patients to examine the impact of differences in the locations of the separated regions on the treatment results. We performed fluoroscopic imaging through the sacral hiatus to assess the condition of adhesions in the epidural space during the post-adhesiolysis observation period.
In patients in whom only the epidural space was separated by adhesiolysis, there was a significant improvement in the Roland-Morris disability questionnaire (RDQ) score until 12 weeks after adhesiolysis, but the score gradually returned to the preoperative value thereafter. Among patients in whom the nerve root responsible for radicular pain was separated, there was a long-term improvement in the RDQ, Oswestry disability index 2.0 (ODI), and Japanese Orthopedic Association Assessment of Treatment (JOA) scores. Among patients in whom both the epidural space and the nerve root responsible for pain were separated, there was a 12 week improvement in the RDQ score and 24 week improvements in the ODI and JOA scores.
Progressive epidural imaging after adhesiolysis suggested that pain was caused by re-adhesion around the nerve root. Since re-adhesion of the nerve root required some time, the effect of adhesiolysis was maintained for extended periods in these cases. We suggest that epiduroscopic adhesiolysis is an effective therapy for FBSS patients, and that adhesiolysis of the nerve root may exhibit the long-term (24 weeks) efficacy in patients with pain.
基于经硬膜外腔镜粘连松解术分离粘连部位,针对腰椎手术失败综合征(FBSS)患者的数据尚未见报道。
我们对28例FBSS患者实施了经硬膜外腔镜粘连松解术,以研究分离区域位置差异对治疗结果的影响。在粘连松解术后观察期,我们通过骶裂孔进行荧光透视成像,以评估硬膜外腔粘连情况。
仅行硬膜外腔粘连松解术的患者,在粘连松解术后12周内罗兰-莫里斯功能障碍问卷(RDQ)评分有显著改善,但此后评分逐渐恢复至术前水平。在分离了引起神经根性疼痛的神经根的患者中,RDQ、奥斯威斯功能障碍指数2.0(ODI)和日本矫形外科学会治疗评估(JOA)评分有长期改善。在硬膜外腔和引起疼痛的神经根均被分离的患者中,RDQ评分在12周时有改善,ODI和JOA评分在24周时有改善。
粘连松解术后的动态硬膜外成像提示,疼痛是由神经根周围重新粘连所致。由于神经根重新粘连需要一定时间,在这些病例中粘连松解术的效果得以长期维持。我们认为经硬膜外腔镜粘连松解术是治疗FBSS患者的有效方法,并且神经根粘连松解术对疼痛患者可能具有长期(24周)疗效。