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多巴酚丁胺负荷超声心动图应变/应变率成像识别罕见的迟发性 Takotsubo 综合征复发中的心肌顿抑。

Myocardial stunning identified by using strain/strain rate imaging during dobutamine stress echocardiography in a rare late recurrence of Tako-Tsubo syndrome.

出版信息

Int J Cardiol. 2010 Nov 5;145(1):e9-12. doi: 10.1016/j.ijcard.2008.12.095. Epub 2009 Jan 27.

Abstract

Tako-Tsubo cardiomyopathy affects postmenopausal women and is often associated to emotional or physical stress. It is typically characterized by transient left ventricular apical ballooning with chest pain and, electrocardiographic changes and biochemical markers suggestive of acute coronary syndrome, despite angiographically normal coronary arteriograms. The pathogenesis of the condition is still unknown, but increased catecholamine levels have been postulated as a pathogenic mechanism. Little data exist in the medical literature regarding recurrent events in this disorder. We present here a case of a 62 year-old woman who had a recurrent episode of Tako-Tsubo syndrome 6 years after initial presentation with typical features of the condition. An underlying cause could not be found that could explain the recurrence of this late episode.

摘要

心尖球囊样综合征影响绝经后妇女,常与情绪或身体应激有关。其典型特征为短暂性左心室心尖气球样变伴胸痛,以及心电图改变和生物化学标志物提示急性冠状动脉综合征,但冠状动脉造影正常。该病的发病机制尚不清楚,但已提出儿茶酚胺水平升高作为一种发病机制。医学文献中关于该病复发性事件的数据很少。我们在此介绍一例 62 岁女性,在最初出现典型心尖球囊样综合征 6 年后再次发生该综合征。未能找到可以解释此次迟发性发作的潜在原因。

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