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一项关于影响长期护理机构中慢性伤口患者伤口愈合因素的回顾性队列研究。

A retrospective cohort study of factors that affect healing in long-term care residents with chronic wounds.

作者信息

Takahashi Paul Y, Kiemele Lester J, Chandra Anupam, Cha Stephen S, Targonski Paul V

机构信息

Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

出版信息

Ostomy Wound Manage. 2009 Jan;55(1):32-7.

Abstract

Chronic ulcers such as pressure, ischemic, and venous ulcers are common in long-term care (LTC) and frequently do not heal. A retrospective medical records review of all LTC residents referred to a wound consultative service between April 1999 and January 2007 was conducted to assess predictors of 6-month healing outcome. Variables abstracted and analyzed included wound, resident demographic, and laboratory values at diagnosis and comorbid medical illnesses. The average age of study participants (n = 397) was 78.1 years (+/- 11), 47% were men, 48% had more than one wound, and the most common wound diagnosis was pressure ulcer (n = 163). After 6 months, 66% of ulcers were not healed. The odds ratio for nonhealing was significantly higher in residents who had more wounds, a larger wound area, diabetes mellitus, or peripheral vascular disease and lower in residents with increased age and hemoglobin values and/or a history of stroke, depression, dementia, degenerative arthritis, peripheral neuropathy, and falls. After adjustment in the multivariate model, only the number of wounds and hemoglobin level remained significant predictors of healing status. A higher number of chronic ulcers and lower hemoglobin counts increased the risk of nonhealing after 6 months of care. Including these variables in LTC resident assessments may help clinicians ascertain expected outcomes of care.

摘要

慢性溃疡,如压疮、缺血性溃疡和静脉性溃疡,在长期护理(LTC)中很常见,且常常难以愈合。对1999年4月至2007年1月间转诊至伤口咨询服务处的所有长期护理机构居民的病历进行回顾性研究,以评估6个月愈合结果的预测因素。提取并分析的变量包括伤口情况、居民人口统计学特征、诊断时的实验室值以及合并的内科疾病。研究参与者(n = 397)的平均年龄为78.1岁(±11岁),47%为男性,48%有一处以上伤口,最常见的伤口诊断为压疮(n = 163)。6个月后,66%的溃疡未愈合。伤口较多、伤口面积较大、患有糖尿病或外周血管疾病的居民不愈合的比值比显著更高,而年龄较大、血红蛋白值较高和/或有中风、抑郁、痴呆、退行性关节炎、外周神经病变和跌倒史的居民不愈合的比值比则较低。在多变量模型中进行调整后,只有伤口数量和血红蛋白水平仍然是愈合状态的显著预测因素。慢性溃疡数量较多且血红蛋白计数较低会增加护理6个月后不愈合的风险。在长期护理机构居民评估中纳入这些变量可能有助于临床医生确定预期的护理结果。

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