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[在腰麻下行择期剖宫产时,氧疗真的有用吗且有必要吗?]

[Is oxygen therapy truly useful and necessary during elective cesarean section under spinal anesthesia?].

作者信息

Palacio F, Ortiz-Gómez J R, Fornet I, Morillas P, Bermejo L, López A

机构信息

Servicio de Anestesiología y Reanimación, Hospital General Universitario Gregorio Marañón, Madrid.

出版信息

Rev Esp Anestesiol Reanim. 2008 Dec;55(10):597-604. doi: 10.1016/s0034-9356(08)70670-4.

Abstract

OBJECTIVE

To analyze maternal and fetal well-being with and without the application of oxygen therapy.

MATERIAL AND METHODS

Randomized trial of full-term parturients who had received prenatal care during pregnancy. The women were healthy and classified as ASA 1. They were scheduled for delivery by cesarean section under spinal anesthesia and randomized to 2 groups to breathe room air or air providing an inspired oxygen fraction of 40% through a face mask. We assessed the well-being of the neonate immediately after birth with the Apgar test and by measuring umbilical cord blood gases.

RESULTS

One hundred thirty women were enrolled. Both groups were similar, with no differences in demographic or hemodynamic variables, time from uterine incision to fetal extraction, neonatal birth weight, presence of umbilical cord abnormalities, type of resuscitation required by the neonate, or Apgar score in the first or fifth minute. Oxygen saturation in maternal blood by pulse oximetry was higher after 10 minutes in the group of women who received supplemental oxygen through face masks. We also observed significant differences in umbilical cord arterial blood between the room air and supplemental oxygen groups, respectively, as follows: PaCO2, 51.14 mm Hg vs 54.33 mm Hg (P=.016); bicarbonate, 22.19 mEq L(-1) vs 23.23 mEq L(-1) (P=.012); lactate, 1.85 mmol L(-1) vs 1.64 mmol L(-1) (P=.038). The PO2 in venous blood also differed significantly: 25.53 mm Hg vs 28.13 mm Hg, respectively (P=033).

CONCLUSIONS

Breathing supplemental oxygen or not during elective cesarean delivery of healthy parturients under spinal anesthesia does not have a significant effect on neonatal well-being.

摘要

目的

分析应用和未应用氧疗时的母婴健康状况。

材料与方法

对孕期接受过产前护理的足月产妇进行随机试验。这些女性身体健康,美国麻醉医师协会(ASA)分级为1级。她们计划在腰麻下行剖宫产分娩,并随机分为两组,一组呼吸室内空气,另一组通过面罩呼吸吸入氧分数为40%的空气。我们在新生儿出生后立即通过阿氏评分和测量脐血气来评估其健康状况。

结果

共纳入130名女性。两组相似,在人口统计学或血流动力学变量、从子宫切开到胎儿娩出的时间、新生儿出生体重、脐带异常情况、新生儿所需复苏类型或第1分钟或第5分钟的阿氏评分方面均无差异。通过脉搏血氧饱和度测定,接受面罩吸氧的女性组在10分钟后母体血液中的氧饱和度更高。我们还观察到室内空气组和吸氧组的脐动脉血之间存在显著差异,具体如下:动脉血二氧化碳分压(PaCO2),51.14毫米汞柱对54.33毫米汞柱(P = 0.016);碳酸氢根,22.19毫当量/升对23.23毫当量/升(P = 0.012);乳酸,1.85毫摩尔/升对1.64毫摩尔/升(P = 0.038)。静脉血中的氧分压(PO2)也有显著差异:分别为25.53毫米汞柱对28.13毫米汞柱(P = 0.033)。

结论

在腰麻下对健康产妇进行择期剖宫产时,呼吸补充氧气与否对新生儿健康状况无显著影响。

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