Samuelsson Olafur, Zoega Helga, Gudmundsson Adalsteinn, Halldorsson Matthias
oldrunarsvidi Landspitala Landakoti, Keykjvik, Iceland.
Laeknabladid. 2009 Jan;95(1):11-7.
To evaluate the prevalence of psychotropic drug use among home-dwelling elderly Icelanders in the year 2006.
A population-based drug utilization study using the Icelandic Medicines Registry. The study group consisted of Icelanders, seventy years and older living at home (8% of total population). Prevalence of antidepressant, neuroleptic, anxiolytic and hypnotic use (ATC-groups N06A, N05A, N05B, N05C) was defined as the dispension per 100 individuals of one or more prescriptions for these drugs within the year 2006. For cross-national comparison we used data for 70-74 year olds in the Danish Registry of Medicinal Product Statistics.
One third of all dispensed prescriptions in Iceland in 2006 were for people aged 70 years and older, and one fourth were for psychotropics. Elderly women were more likely than men to use psychotropics (RR=1.40 95% CI: 1.37-1.43). The prevalence of psychotropic use was 65.5% for women and 46.8% for men. Anxiolytics and hypnotics (N05B or N05C) were the most frequently used psychotropics, with a prevalence of 58.5% for women and 40.3% for men. Antidepressants were used by 28.8 % of women and 18.4 % of men. Neuroleptics were used by 5%. By comparing 70-74 years old Icelanders and Danes, the Icelanders were 1.5 to 2.5 times more likely to receive any psychotropics drug in 2006.
Use of psychotropics, especially anxiolytics and hypnotics, is common among elderly Icelanders. Comparing information for 70 to 74 year olds with Danes of same age, the prescribing of psychotropics is more frequent in Iceland.
评估2006年冰岛居家老年人中精神药物的使用情况。
一项基于冰岛药品登记处的人群药物利用研究。研究组由70岁及以上的居家冰岛人组成(占总人口的8%)。抗抑郁药、抗精神病药、抗焦虑药和催眠药的使用情况(解剖学治疗学及化学分类系统分组N06A、N05A、N05B、N05C)定义为2006年每100人中开具一种或多种此类药物处方的配药情况。为进行跨国比较,我们使用了丹麦药品统计登记处中70 - 74岁人群的数据。
2006年冰岛所有配药处方中有三分之一是给70岁及以上人群的,四分之一是精神药物。老年女性比男性更有可能使用精神药物(相对危险度=1.40,95%置信区间:1.37 - 1.43)。女性精神药物使用率为65.5%,男性为46.8%。抗焦虑药和催眠药(N05B或N05C)是最常用的精神药物,女性使用率为58.5%,男性为40.3%。28.8%的女性和18.4%的男性使用抗抑郁药。5%的人使用抗精神病药。通过比较70 - 74岁的冰岛人和丹麦人,2006年冰岛人接受任何精神药物治疗的可能性是丹麦人的1.5至2.5倍。
精神药物,尤其是抗焦虑药和催眠药,在冰岛老年人中使用很普遍。将70至74岁人群的信息与同龄丹麦人相比,冰岛精神药物的处方开具更为频繁。