Brink M, Kool D R, Dekker H M, Deunk J, Jager G J, van Kuijk C, Edwards M J R, Blickman J G
Department of Radiology, Radboud University Nijmegen Medical Centre, The Netherlands.
Clin Radiol. 2009 Mar;64(3):272-83. doi: 10.1016/j.crad.2008.09.004. Epub 2008 Nov 13.
To identify and to evaluate predictors that determine whether chest computed tomography (CT) is likely to reveal relevant injuries in adult blunt trauma patients.
After a comprehensive literature search for original studies on blunt chest injury diagnosis, two independent observers included studies on the accuracy of parameters derived from history, physical examination, or diagnostic imaging that might predict injuries at (multidetector row) CT in adults and that allowed construction of 2x2 contingency tables. For each article, methodological quality was scored and relevant predictors for injuries at CT were extracted. For each predictor, sensitivity, specificity, positive and negative likelihood ratio and diagnostic odds ratio (DOR) including 95% confidence intervals were calculated.
Of 147 articles initially identified, the observers included 10 original studies in consensus. Abnormalities at physical examination (abnormal respiratory effort, need for assisted ventilation, reduced airentry, coma, chest wall tenderness) and pelvic fractures were significant predictors (DOR: 2.1-6.7). The presence of any injuries at conventional radiography of the chest (eight articles) was a more powerful significant predictor (DOR: 2.2-37). Abnormal chest ultrasonography (four articles) was the most accurate predictor for chest injury at CT (DOR: 491-infinite).
The current literature indicates that in blunt trauma patients with abnormal physical examination, abnormal conventional radiography, or abnormal ultrasonography of the chest, CT was likely to reveal relevant chest injuries. However, there was no strong evidence to suggest that CT could be omitted in patients without these criteria, or whether these findings are beneficial for patients.
识别并评估可判定胸部计算机断层扫描(CT)是否可能在成年钝性创伤患者中发现相关损伤的预测因素。
在对钝性胸部损伤诊断的原始研究进行全面文献检索后,两名独立观察者纳入了关于源自病史、体格检查或诊断成像的参数准确性的研究,这些参数可能预测成人(多层螺旋)CT检查中的损伤,并且允许构建2×2列联表。对于每篇文章,对方法学质量进行评分,并提取CT检查中损伤的相关预测因素。对于每个预测因素,计算敏感性、特异性、阳性和阴性似然比以及诊断比值比(DOR),包括95%置信区间。
在最初识别的147篇文章中,观察者一致纳入了10项原始研究。体格检查异常(呼吸努力异常、需要辅助通气、呼吸音减弱、昏迷、胸壁压痛)和骨盆骨折是显著的预测因素(DOR:2.1 - 6.7)。胸部传统X线摄影(8篇文章)中存在任何损伤是一个更强有力的显著预测因素(DOR:2.2 - 37)。胸部超声检查异常(4篇文章)是CT检查中胸部损伤最准确的预测因素(DOR:491 - 无穷大)。
当前文献表明,在体格检查异常、传统X线摄影异常或胸部超声检查异常的钝性创伤患者中,CT可能会发现相关的胸部损伤。然而,没有强有力的证据表明在没有这些标准的患者中可以省略CT检查,或者这些发现对患者是否有益。