Boczek-Funcke A, Häbler H J, Jänig W, Michaelis M
Physiologisches Institut der Universität, Christian-Albrechts-Universität, Kiel, F.R.G.
J Auton Nerv Syst. 1991 Jun 15;34(2-3):185-94. doi: 10.1016/0165-1838(91)90084-g.
We tested the hypothesis that the inhibitory influence of rapid phasic arterial baroreceptor stimulation on activity in sympathetic preganglionic neurones is weaker in inspiration than in expiration. Using neurophysiological techniques, 59 single preganglionic neurones with typical reflex pattern of muscle vasoconstrictor neurones that projected in the cervical sympathetic trunk were analysed. The inhibitory modulation of the ongoing activity in these neurones by the pulsatile activation of the arterial baroreceptors was determined by constructing post-R-wave histograms separately for both respiratory phases (as indicated by the discharge in the phrenic nerve). Quantitative measurements showed that the inhibition of the activity in the preganglionic neurones following phasic stimulation of arterial baroreceptors by the pulse pressure wave was not statistically different in both respiratory phases, even with increased respiratory drive.
快速阶段性动脉压力感受器刺激对交感神经节前神经元活动的抑制作用在吸气时比呼气时弱。我们运用神经生理学技术，分析了59个投射至颈交感干的具有典型肌肉血管收缩神经元反射模式的单个节前神经元。通过分别针对两个呼吸阶段（由膈神经放电指示）构建R波后直方图，确定动脉压力感受器的搏动性激活对这些神经元持续活动的抑制性调制。定量测量结果显示，即使呼吸驱动增强，在两个呼吸阶段中，脉压波对动脉压力感受器进行阶段性刺激后，节前神经元活动受到的抑制在统计学上并无差异。
