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消除碘缺乏病——印度西孟加拉邦普尔巴梅迪尼布尔区的现状

Elimination of iodine deficiency disorders--current status in Purba Medinipur district of West Bengal, India.

作者信息

Biswas A B, Chakraborty I, Das D K, Chakraborty A, Ray D, Mitra K

机构信息

B. S. Medical College, Bankura.

出版信息

Indian J Public Health. 2008 Jul-Sep;52(3):130-5.

Abstract

BACKGROUND AND OBJECTIVES

Towards sustainable elimination of iodine deficiency disorders (IDD), the existing programme needs to be monitored through recommended methods and indicators. Thus, we conducted the study to assess the current status of IDD in Purba Medinipur district, West Bengal.

METHODS

It was a community based cross-sectional study; undertaken from October 2006-April 2007. 2400 school children, aged 8-10 years were selected by '30 cluster' sampling technique. Indicators recommended by the WHO/UNICEF/ICCIDD were used. Subjects were clinically examined by standard palpation technique for goitre, urinary iodine excretion was estimated by wet digestion method and salt samples were tested by spot iodine testing kit.

RESULTS

The total goitre rate (TGR) was 19.7% (95% CI = 18.1-21.3 %) with grade I and grade II (visible goitre) being 16.7% and 3% respectively. Goitre prevalence did not differ by age but significant difference was observed in respect of sex. Median urinary iodine excretion level was 11.5 mcg/dL and none had value less than 5 mcg/dL. Only 50.4% of the salt samples tested were adequately iodised (> or = 15 ppm).

CONCLUSION

The district is in a phase of transition from iodine deficiency to iodine sufficiency as evident from the high goitre prevalence (19.7%) and median urinary iodine excretion (11.5 mcg/dL) within optimum limit. But, salt iodisation level far below the recommended goal highlights the need for intensified efforts towards successful transition.

摘要

背景与目的

为了实现碘缺乏病(IDD)的可持续消除,需要通过推荐的方法和指标对现有项目进行监测。因此,我们开展了这项研究,以评估西孟加拉邦普尔巴梅迪尼布尔区碘缺乏病的现状。

方法

这是一项基于社区的横断面研究;于2006年10月至2007年4月进行。采用“30个群组”抽样技术选取了2400名8至10岁的学童。使用了世界卫生组织/联合国儿童基金会/国际控制碘缺乏病理事会推荐的指标。通过标准触诊技术对受试者进行临床甲状腺肿检查,采用湿消化法估计尿碘排泄量,并使用碘快速检测试剂盒对盐样进行检测。

结果

总甲状腺肿率(TGR)为19.7%(95%置信区间=18.1 - 21.3%),其中I级和II级(可见甲状腺肿)分别为16.7%和3%。甲状腺肿患病率在年龄上无差异,但在性别方面存在显著差异。尿碘排泄中位数水平为11.5微克/分升,且没有人的值低于5微克/分升。所检测的盐样中只有50.4%的碘含量充足(≥15 ppm)。

结论

从高甲状腺肿患病率(19.7%)和处于最佳限度内的尿碘排泄中位数(11.5微克/分升)可以明显看出,该地区正处于从碘缺乏向碘充足过渡的阶段。但是,盐碘强化水平远低于推荐目标,这凸显了加大力度以成功实现过渡的必要性。

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