Si Satyabrata, Dinda Enakshi, Mandal Tarun K
Polymer Science Unit and Centre for Advanced Materials, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.
J Nanosci Nanotechnol. 2008 Nov;8(11):5934-41. doi: 10.1166/jnn.2008.260.
An oligopeptide with a free amino group at the N-terminus and a redox active tryptophan residue at the C-terminus was used to synthesize gold nanocrystals of different shapes. The concentration ratio of peptide to HAuCl4 has a significant effect on the shape of the formed nanocrystals and the polyhedral gold nanocrystals are mainly formed at higher such ratio. The effect of medium pH and reaction temperature on the shape of the formed gold nanocrystals has also been investigated. However, an oligopeptide with blocked amino group with tert-butyloxycarbonyl group resulted only spherical gold nanocrystals along with some aggregated structures. A probable mechanism for the formation of polyhedral gold nanocrystals has been described, which indicate the presence of multiple anchoring sites in the peptide molecules is mainly responsible for this type of crystal growth. The formed nanocrystals were well characterized by various experimental techniques like, UV-visible spectroscopy, transmission electron microscopy, and X-ray diffraction.
一种在N端带有游离氨基且在C端带有氧化还原活性色氨酸残基的寡肽被用于合成不同形状的金纳米晶体。肽与HAuCl4的浓度比对所形成纳米晶体的形状有显著影响，并且在较高的该比例下主要形成多面体金纳米晶体。还研究了介质pH值和反应温度对所形成金纳米晶体形状的影响。然而，一种氨基被叔丁氧羰基封闭的寡肽仅产生球形金纳米晶体以及一些聚集结构。已经描述了多面体金纳米晶体形成的一种可能机制，这表明肽分子中多个锚定位点的存在是这种晶体生长类型的主要原因。所形成的纳米晶体通过紫外可见光谱、透射电子显微镜和X射线衍射等各种实验技术进行了很好的表征。
