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一名血液透析患者发生后纵隔脓肿——一种罕见但危及生命的葡萄球菌血症并发症。

Posterior mediastinal abscess in a hemodialysis patient - a rare but life-threatening complication of Staphylococcus bacteremia.

作者信息

Chang C H, Huang J Y, Lai P C, Yang C W

机构信息

Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, School of Medicine, Chang Gung University, Taiwan.

出版信息

Clin Nephrol. 2009 Jan;71(1):92-5. doi: 10.5414/cnp71092.

Abstract

Mediastinal abscess is a rare but life-threatening disease with grave prognosis if not recognized in time. The diagnosis of this entity is hampered by its nonspecific presentation. Thus, a high index of clinical suspicion is one of the keystones in the successful management of these patients. Currently, mediastinitis occurred mostly as a complication post cardiovascular or thoracic surgical procedures. Rarely, primary mediastinitis developed as a result of hematogenous spread. We report the case of primary mediastinitis in a renal failure patient who had Staphylococcus aureus bacteremia. Despite antibiotic treatment, she had massive hemoptysis and eventually succumbed to the disease. To our knowledge, this is the first report of Staphylococcus aureus bacteremia complicating mediastinal abscess in a dialysis patient with a native arteriovenous shunt. Our experience in this case suggests that dialysis patients are under constant risk of staphylococcal infection due to regular venous puncture. Measures should be taken to reduce the risk and staphylococcal infection should not be forgotten in any dialysis patient with fever of unknown origin.

摘要

纵隔脓肿是一种罕见但危及生命的疾病,如果不及时识别,预后严重。该疾病的诊断因其非特异性表现而受到阻碍。因此,高度的临床怀疑是成功治疗这些患者的关键之一。目前,纵隔炎大多作为心血管或胸外科手术后的并发症出现。很少有原发性纵隔炎是血行播散所致。我们报告了一例患有金黄色葡萄球菌菌血症的肾衰竭患者发生原发性纵隔炎的病例。尽管进行了抗生素治疗,她仍出现大量咯血,最终死于该疾病。据我们所知,这是首例在患有自体动静脉分流的透析患者中,金黄色葡萄球菌菌血症并发纵隔脓肿的报告。我们在该病例中的经验表明,由于定期静脉穿刺,透析患者持续面临葡萄球菌感染的风险。应采取措施降低风险,对于任何不明原因发热的透析患者,都不应忽视葡萄球菌感染。

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