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[腹腔镜检查在卵巢癌中的作用]

[The role of laparoscopy in ovarian carcinoma].

作者信息

Angioli R, Muzii L, Battista C, Terranova C, Oronzi I, Sereni M I, De Oronzo M A, Damiani P, Collettini F, Graziano M, Benedetti Panici P

机构信息

Dipartimento di Ostetricia e Ginecologia, Università Campus Bio-Medico di Roma, Roma, Italia.

出版信息

Minerva Ginecol. 2009 Feb;61(1):35-43.

Abstract

The role of minimally invasive surgery in the management of gynecologic cancers is continuously expanding. Although few trials have focused on the safety of laparoscopy in oncology, laparoscopy is now widely used for most gynecological malignancies. Laparoscopy is widely used to manage benign ovarian masses, but its role in managing ovarian cancer still needs to be defined. The role of laparoscopy in ovarian cancer surgery may be divided into three following categories: 1) laparoscopic staging of apparent early ovarian cancer; 2) laparoscopic assessment of disease extent and potential for resectability; 3) laparoscopic reassessment, or second-look operation, or rule out recurrence. Laparoscopic approach has shown several advantages like a reduction in operating time, blood loss, hospital stay, and total hospital charges. The limitations of laparoscopic practice include inadequate port-site metastasis, tumour dissemination due to cyst rupture and incomplete staging. In addition, there were limitations in performing extensive laparoscopic sampling of areas of tumor persistence including retroperitoneal lymph nodes. In literature there are no randomized studies assessing the use of laparoscopy in the management of ovarian cancer. Moreover, most of the studies in literature comparing laparoscopy and laparotomy are carried out by surgeons specialized in one of two approaches, so that the results can not be compared.

摘要

微创手术在妇科癌症治疗中的作用正在不断扩大。尽管很少有试验关注腹腔镜手术在肿瘤学中的安全性,但腹腔镜手术目前已广泛应用于大多数妇科恶性肿瘤的治疗。腹腔镜手术广泛用于处理良性卵巢肿块,但其在卵巢癌治疗中的作用仍有待明确。腹腔镜手术在卵巢癌手术中的作用可分为以下三类:1)对明显早期卵巢癌进行腹腔镜分期;2)对疾病范围和可切除性潜力进行腹腔镜评估;3)腹腔镜再次评估、二次探查手术或排除复发。腹腔镜手术方法已显示出一些优势,如手术时间缩短、失血减少、住院时间缩短和总住院费用降低。腹腔镜手术的局限性包括端口部位转移不足、因囊肿破裂导致肿瘤播散以及分期不完整。此外,在对包括腹膜后淋巴结在内的肿瘤持续存在区域进行广泛的腹腔镜取样方面存在局限性。文献中没有评估腹腔镜手术在卵巢癌治疗中应用的随机研究。此外,文献中大多数比较腹腔镜手术和开腹手术的研究是由擅长这两种手术方法之一的外科医生进行的,因此结果无法进行比较。

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