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小麦草疗法对重型β地中海贫血输血需求的影响。

Effect of wheat grass therapy on transfusion requirement in beta-thalassemia major.

作者信息

Choudhary Dharma R, Naithani Rahul, Panigrahi Inusha, Kumar Rajat, Mahapatra Manoranjan, Pati Hara Prasad, Saxena Renu, Choudhry Ved P

机构信息

Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Pediatr. 2009 Apr;76(4):375-6. doi: 10.1007/s12098-009-0004-6. Epub 2009 Feb 10.

DOI:10.1007/s12098-009-0004-6
PMID:19205635
Abstract

OBJECTIVE

To assess the efficacy of wheat grass juice on transfusion requirement in patients with beta thalassemia major.

METHODS

Fifty-three patients of thalassemia major with a median age of 16 years were given wheat grass juice tablets.

RESULTS

The Mean pre and post wheat grass therapy, the pack cell requirement was 288.06 +/- 53.25 gm/Kg/year and 301.25 +/- 54.86 gm/Kg/year (p =0.054) respectively. No adverse effects were noted.

CONCLUSION

We conclude that wheat grass therapy for one year is not effective in reducing the transfusion requirement in transfusion dependent thalassemia.

摘要

目的

评估小麦草汁对重型β地中海贫血患者输血需求的疗效。

方法

53例重型地中海贫血患者,中位年龄16岁,给予小麦草汁片。

结果

小麦草治疗前后,平均红细胞压积需求分别为288.06±53.25克/千克/年和301.25±54.86克/千克/年(p = 0.054)。未观察到不良反应。

结论

我们得出结论,为期一年的小麦草治疗对减少依赖输血的地中海贫血患者的输血需求无效。

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本文引用的文献

1
Fermented Wheat Germ Extract Reduces Chemotherapy-Induced Febrile Neutropenia in Pediatric Cancer Patients.发酵小麦胚芽提取物可降低小儿癌症患者化疗引起的发热性中性粒细胞减少症。
J Pediatr Hematol Oncol. 2004 Oct;26(10):631-635. doi: 10.1097/01.mph.0000141897.04996.21.
2
Wheat grass juice reduces transfusion requirement in patients with thalassemia major: a pilot study.小麦草汁可降低重型地中海贫血患者的输血需求:一项初步研究。
Indian Pediatr. 2004 Jul;41(7):716-20.
3
Hydroxyurea can eliminate transfusion requirements in children with severe beta-thalassemia.
羟基脲可以消除重度β地中海贫血患儿的输血需求。
Blood. 2003 Aug 15;102(4):1529-30. doi: 10.1182/blood-2003-01-0117. Epub 2003 Apr 17.
4
Long-term hydroxyurea therapy in beta-thalassaemia patients.β地中海贫血患者的长期羟基脲治疗
Eur J Haematol. 2003 Mar;70(3):151-5. doi: 10.1034/j.1600-0609.2003.00037.x.
5
Wheat grass juice in the treatment of active distal ulcerative colitis: a randomized double-blind placebo-controlled trial.小麦草汁治疗活动期远端溃疡性结肠炎:一项随机双盲安慰剂对照试验。
Scand J Gastroenterol. 2002 Apr;37(4):444-9. doi: 10.1080/003655202317316088.