贾第虫病所致症状性缺铁性贫血与十二指肠结节性淋巴组织增生并存：病例报告

Coexistence of symptomatic iron-deficiency anemia and duodenal nodular lymphoid hyperplasia due to giardiasis: case report.

作者信息

Kasirga Erhun, Gülen Hüseyin, Simşek Ayşe, Ayhan Semin, Yilmaz Ozge, Ellidokuz Ender

机构信息

Celal Bayar University Faculty of Medicine, Manisa, Turkey.

出版信息

Pediatr Hematol Oncol. 2009 Jan;26(1):57-61. doi: 10.1080/08880010802243987.

DOI:10.1080/08880010802243987

PMID:19206009

Abstract

Iron-deficiency anemia due to iron malabsorption and duodenal nodular lymphoid hyperplasia (NLH) has been described in children with Giardia intestinalis infection. Also, symptomatic iron-deficiency anemia is rarely encountered in male adolescents. A 14-year-old boy underwent esophagogastroduodenoscopy for investigation of symptomatic iron-deficiency anemia (hemoglobin 5.8 g/dL, mean corpuscular volume 65.3 fL, serum ferritin < 1.5 ng/mL). He had a sufficient diet for iron and recurrent bouts of diarrhea without melena. At upper endoscopy, duodenal mucosa was diffusely nodular. Histopathologic evaluation of biopsy samples from the duodenum revealed infection with Giardia intestinalis. His anemia improved with metronidazole and iron treatment.

摘要

因铁吸收不良和十二指肠结节性淋巴样增生（NLH）导致的缺铁性贫血在感染肠道贾第鞭毛虫的儿童中已有报道。此外，有症状的缺铁性贫血在男性青少年中很少见。一名14岁男孩因有症状的缺铁性贫血（血红蛋白5.8 g/dL，平均红细胞体积65.3 fL，血清铁蛋白<1.5 ng/mL）接受了食管胃十二指肠镜检查。他摄入了充足的含铁饮食，有反复腹泻但无黑便。上消化道内镜检查时，十二指肠黏膜呈弥漫性结节状。十二指肠活检样本的组织病理学评估显示感染了肠道贾第鞭毛虫。甲硝唑和铁剂治疗后他的贫血症状有所改善。