Sławińska A, Siwek M, Knol E F, Roelofs-Prins D T, van Wijk H J, Dibbits B, Bednarczyk M
Department of Animal Biotechnology, University of Technology and Life Sciences, Bydgoszcz, Poland.
J Anim Breed Genet. 2009 Feb;126(1):43-51. doi: 10.1111/j.1439-0388.2008.00753.x.
Porcine chromosome 4 harbours many quantitative trait loci (QTL) affecting meat quality, fatness and carcass composition traits, detected in resource pig populations previously. However, prior to selection in commercial breeds, QTL identified in an intercross between divergent breeds require confirmation, so that they can be segregated. Consequently, the objective of this study was to validate several QTL on porcine chromosome 4 responsible for meat and carcass quality traits. The experimental population consisted of 14 crossbred paternal half-sib families. The region of investigation was the q arm of SSC4 flanked by the markers S0073 and S0813. Regression analysis resulted in the validation of three QTL within the interval: Minolta a* loin, back fat thickness and the weight of trimmed ham. The results were additionally confirmed by factor analysis. Candidate genes were proposed for meat colour, which was the most evident QTL validated in this study.
猪的4号染色体含有许多影响肉质、脂肪含量和胴体组成性状的数量性状基因座（QTL），这些基因座先前在资源猪群体中已被检测到。然而，在商业品种进行选育之前，在不同品种间杂交中鉴定出的QTL需要进行验证，以便它们能够被分离出来。因此，本研究的目的是验证猪4号染色体上几个与肉和胴体品质性状相关的QTL。实验群体由14个杂交父本半同胞家系组成。研究区域是猪4号染色体q臂，两侧标记为S0073和S0813。回归分析结果验证了该区间内的三个QTL：Minolta a*值（腰肉色）、背膘厚度和去骨火腿重量。因子分析进一步证实了这些结果。本研究中验证的最明显的QTL是肉色，为此提出了候选基因。
