Huang Shao, Fabian James, Murray Timothy, Shi Wei
Bascom Palmer Eye Institute, Miami, Florida, USA.
Optom Vis Sci. 2009 Mar;86(3):286-9. doi: 10.1097/OPX.0b013e318196a724.
To report visual acuity (VA) outcomes in eyes undergoing photodynamic therapy (PDT), with or without concurrent intravitreal Triamcinolone acetonide (IVTA), for symptomatic circumscribed choroidal hemangioma.
We retrospectively reviewed clinical records of 16 patient treated from January 2001 to May 2006. Post-treatment Snellen VA was compared with pretreatment measurements.
Ten eyes underwent only PDT therapy, in which VA in three eyes improved by more than two lines and seven eyes remained stable. Four eyes were treated with combined PDT and IVTA. VA in two of those eyes improved more than 2 lines, one eye remained stable, and one eye worsened at most recent follow-up. Another two eyes failed initial treatment elsewhere and were not included in the final analysis.
VA outcome is generally good in patients treated with PDT alone. This study was limited by a small sample size of PDT/IVTA treatment group, therefore, we could not compare outcomes to the PDT alone treatment.
报告接受光动力疗法(PDT)治疗有症状的局限性脉络膜血管瘤的患者的视力(VA)结果,无论是否同时玻璃体腔内注射曲安奈德(IVTA)。
我们回顾性分析了2001年1月至2006年5月期间治疗的16例患者的临床记录。将治疗后的斯内伦视力与治疗前的测量结果进行比较。
10只眼仅接受了PDT治疗,其中3只眼的视力提高了两行以上,7只眼保持稳定。4只眼接受了PDT联合IVTA治疗。其中2只眼的视力提高了2行以上,1只眼保持稳定,1只眼在最近一次随访时视力恶化。另外2只眼在其他地方初始治疗失败,未纳入最终分析。
单独接受PDT治疗的患者视力结果总体良好。本研究因PDT/IVTA治疗组样本量小而受到限制,因此,我们无法将结果与单独PDT治疗进行比较。