Chiang Ying-Yi, Tsai Hsiou-Hsin, Lee Woan-Ruoh, Wang Kuo-Hsien
Department of Dermatology, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan.
J Cutan Pathol. 2009 Mar;36(3):381-4. doi: 10.1111/j.1600-0560.2008.01038.x.
Clear cell fibrous papule (FP) is a rare variant of FP. We report a 39-year-old female patient who presented with a dome-shaped papule on the nose. The diagnosis of clear cell FP was made based on histological and immunohistochemical studies. Interestingly, scattered S-100 cells were admixed within the lesion, a finding hitherto not reported. The S-100 positivity may be misleading and should be cautiously interpreted.