阿尔茨海默病研究:该领域前100名研究人员的科研产出与影响力

Alzheimer's disease research: scientific productivity and impact of the top 100 investigators in the field.

作者信息

Sorensen Aaron A

机构信息

Collexis Holdings, Inc., Life Science Solutions Leader, Europe, Via Bramantino 1, 6600 Locarno, Switzerland.

出版信息

J Alzheimers Dis. 2009;16(3):451-65. doi: 10.3233/JAD-2009-1046.

Abstract

The online availability of scientific-literature databases and natural-language-processing (NLP) algorithms has enabled large-scale bibliometric studies within the field of scientometrics. Using NLP techniques and Thomson ISI reports, an initial analysis of the role of Alzheimer's disease (AD) within the neurosciences as well as a summary of the various research foci within the AD scientific community are presented. Citation analyses and productivity filters are applied to post-1984, AD-specific subsets of the PubMed and Thomson ISI Web-of-Science literature bases to algorithmically identify a pool of the top AD researchers. From the initial pool of AD investigators, top-100 rankings are compiled to assess productivity and impact. One of the impact and productivity metrics employed is an AD-specific H-index. Within the AD-specific H-index ranking, there are many cases of multiple AD investigators with similar or identical H-indices. In order to facilitate differentiation among investigators with equal or near-equal H indices, two derivatives of the H-index are proposed: the Second-Tier H-index and the Scientific Following H-index. Winners of two prestigious AD-research awards are highlighted, membership to the Institute of Medicine of the US National Academy of Sciences is acknowledged, and an analysis of highly-productive, high-impact, AD-research collaborations is presented.

摘要

科学文献数据库和自然语言处理(NLP)算法的在线可用性推动了科学计量学领域的大规模文献计量研究。利用NLP技术和汤姆森ISI报告,对阿尔茨海默病(AD)在神经科学领域中的作用进行了初步分析,并总结了AD科学界内的各种研究重点。引用分析和生产力筛选应用于1984年以后PubMed和汤姆森ISI科学网文献库中特定于AD的子集,以通过算法识别出一批顶尖的AD研究人员。从最初的AD研究人员库中,编制了前100名排名,以评估生产力和影响力。所采用的影响力和生产力指标之一是特定于AD的H指数。在特定于AD的H指数排名中,有许多AD研究人员具有相似或相同H指数的情况。为了便于区分H指数相等或接近相等的研究人员,提出了H指数的两个衍生指标:二级H指数和科学追随H指数。突出了两项著名AD研究奖项的获得者,认可了美国国家科学院医学研究所的成员资格,并对高生产力、高影响力的AD研究合作进行了分析。

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