蛋白质缺乏对大鼠体内α-生育酚吸收、转运及分布的影响。

Effect of protein deficiency on absorption, transport and distribution of alpha-tocopherol in the rat.

作者信息

Rajaram O V, Fatterpaker P, Sreenivasan A

出版信息

Br J Nutr. 1977 Mar;37(2):157-65. doi: 10.1079/bjn19770018.

DOI:10.1079/bjn19770018

PMID:192264

Abstract

The absorption, transport and distribution of alpha-[3H]tocopherol were greatly decreased in protein deficiency. This was reflected in the subcellular distribution of alpha-[3H]tocopherol in livers of protein-deficient rats. The ratio, bound:free for alpha-[3H]tocopherol, also decreased in both serum and liver cytosol. After protein refeeding, absorption, transport and distribution patterns of alpha-[3H]tocopherol for the protein-deficient rats were restored to patterns similar to those of control animals.

摘要

蛋白质缺乏时，α-[3H]生育酚的吸收、转运和分布显著减少。这在蛋白质缺乏大鼠肝脏中α-[3H]生育酚的亚细胞分布上得到体现。血清和肝细胞溶质中α-[3H]生育酚的结合态与游离态之比也降低。重新喂食蛋白质后，蛋白质缺乏大鼠的α-[3H]生育酚吸收、转运和分布模式恢复到与对照动物相似的模式。