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影像学中的意外发现:预测各种类型研究中的频率。

Unexpected findings at imaging: predicting frequency in various types of studies.

机构信息

Public Health Department, Miguel Hernández University, Spain; CIBER en Epidemiología y Salud Pública, Spain.

出版信息

Eur J Radiol. 2010 Apr;74(1):269-74. doi: 10.1016/j.ejrad.2009.01.029. Epub 2009 Feb 23.

Abstract

OBJECTIVE

: The objective was to evaluate the prevalence and associated variables of unsuspected findings from imaging tests in clinical practice.

MATERIAL AND METHODS

: Cross-sectional study of patients referred for an imaging test in 2006. Two independent radiologists classified the imaging tests according to the presence or absence of an unexpected finding in relation with the causes that prompted the test (kappa=0.95). A thorough chart review of these patients was carried out as a quality control.

RESULTS

: Out of 3259 patients in the study, 488 revealed unsuspected findings (15.0%). The prevalence of abnormal findings varied according to age: from 20.4% (150/734) in the over 74-group to 9.0% (76/847) in the under 43-group. The largest prevalence was in the category of infectious diseases (14/49, 28.6%) and in CT (260/901, 28.9%) and ultrasound (138/668, 20.7%). Studies showing moderate clinical information on the referral form were less likely to show unexpected findings than those with null or minor information (OR 0.51; 95% CI 0.36-0.73).

CONCLUSION

: Clinicians should expect the frequency of diseases detectable by imaging to increase in the future. Further research with follow-up of these findings is needed to estimate the effect of imaging technologies on final health outcomes.

摘要

目的

评估临床实践中影像检查未预期发现的发生率及其相关变量。

材料与方法

对 2006 年进行影像检查的患者进行横断面研究。两名独立的放射科医生根据与检查原因相关的存在或不存在意外发现,对影像检查进行分类(kappa=0.95)。对这些患者进行了详细的病历回顾,作为质量控制。

结果

在研究的 3259 名患者中,488 名患者有未预期的发现(15.0%)。异常发现的患病率因年龄而异:74 岁以上组为 20.4%(150/734),43 岁以下组为 9.0%(76/847)。发病率最高的是传染病类别(14/49,28.6%),CT(260/901,28.9%)和超声(138/668,20.7%)。与仅有少量或无临床信息的转诊表相比,显示中度临床信息的研究更不可能发现未预期的发现(OR 0.51;95% CI 0.36-0.73)。

结论

临床医生应预计未来可通过影像学检测到的疾病的频率会增加。需要进一步进行这些发现的随访研究,以评估影像学技术对最终健康结果的影响。

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